Antimalarial combination therapies increase gastric ulcers through an imbalance of basic antioxidative-oxidative enzymes in male Wistar rats

Table 1 Multiple comparisons on ulcer index, malondialdehyde, and reduced glutathione in male Wistar rats for against each experimental group

Tukey’s multiple comparisons tests	Ulcer index	Malondialdehyde	Reduced glutathione
Tukey’s multiple comparisons tests	Adjusted P values
Artesunate vs. Artesunate-amodiaquine	0.6887	< 0.0001	< 0.0001
Artesunate vs. Artemether-lumefantrine	0.8519	< 0.0001	< 0.0001
Artesunate vs. positive control	< 0.0001	< 0.0003	0.0166
Artesunate vs. negative control	> 0.9999	0.0685	0.9973
Artesunate-amodiaquine vs. Artemether-lumefantrine	0.9982	0.9997	0.9701
Artesunate-amodiaquine vs. positive control	< 0.0001	< 0.0001	0.0348
Artesunate-amodiaquine vs. negative control	0.7211	< 0.0001	< 0.0001
Artemether-lumefantrine vs. positive control	< 0.0001	< 0.0001	0.1009
Artemether-lumefantrine vs. negative control	0.8704	< 0.0001	< 0.0001
Positive control vs. negative control	< 0.0001	< 0.0001	0.0118

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