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Fig. 2 | BMC Research Notes

Fig. 2

From: Expression of the miR-200 family in tumor tissue, plasma and urine of epithelial ovarian cancer patients in comparison to benign counterparts

Fig. 2

a Relative levels of miR-200a, miR-200b and miR-200c between malignant and benign samples. b Correlation of expression levels between plasma, urine and tumor tissue samples. a Relative expression of miR-200a, miR-200b and miR-200c in plasma and tissue are significantly higher in malignant samples compared to benign. The difference is not significant in urine samples (** p < 0.001, *** p < 0.0001). b Combined scatter plots showing correlations of relative expression for all three miRNAs (miR-200a (black dots), miR-200b (red dots) and miR-200c (green dots)) between plasma, urine and tumor tissue samples of HGSOC patients (Pearson’s rank correlation coefficient). For plasma and urine two replicates per sample were available, but for tissue variable numbers of replicates were available. Thus, the correlation plot for urine vs plasma was done replicate by replicate, but the correlation plots Tissue vs Plasma and Tissue vs Urine were done on average values one-to-one, explaining fewer dots in these plots. Pearson’s ranks for small sample size of individual miR-200a, miR-200b, or miR-200c did not reach significance (data not shown)

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