Smoking habit and chemo-radiotherapy and/or surgery affect the sensitivity of EGFR plasma test in non-small cell lung cancer

Table 2 Influential factors for the sensitivity in multivariable analysis

Variable	OR (95%CI)	P-value
Ecog PS: ≥ 2 versus 0–1	4.81 (0.59–46.80)	0.176
Smoking habit: Yes versus No	0.24 (0.07–0.79)	0.019
Pleural effusion: Yes versus No	1.09 (0.26–4.56)	0.911
Tumor size: > 5 cm versus ≤ 5 cm	1.79 (0.51–6.32)	0.366
Treatment history: Yes versus No	0.36 (0.10–0.91)	0.047

In the logistic regression analysis, patients with EGFR mutations in both tumor tissue and plasma were coded 1, while the positive cases only in the tumor tissue were coded 0; other factors were coded 1: Ecog PS ≥ 2, smoking habit = yes, pleural effusion = yes, tumor size > 5 cm, and treatment history = yes; the remaining groups of factors were coded 0
Significant values are shown in italic

ISSN: 1756-0500