Polymorphisms of brain-derived neurotrophic factor genes are associated with anxiety and body mass index in fibromyalgia syndrome patients

Table 1 Demographic of HC and FMS patients

Variables	HCs (n = 42)	FMS patients (n = 72)	p^#
Age (years-old)	53.12 ± 0.83	54.19 ± 1.10	0.495
Pain (VAS)	0.95 ± 0.20	6.11 ± 0.21	< 0.000
Fatigue (VAS)	1.80 ± 0.36	6.36 ± 0.23	< 0.000
Anxiety (HADS-A)	4.62 ± 0.56	9.75 ± 0.44	< 0.000
Depression (HADS-D)	2.81 ± 0.50	8.16 ± 0.46	< 0.000
BMI (kg/m²)	24.80 ± 0.57	27.70 ± 0.63	0.001
No. tender points	–	15.39 ± 0.27	–
Disease duration (years)	–	7.29 ± 0.59	–

BMI body mass index, FMS fibromyalgia syndrome, HADS Hospital Anxiety and Depression Scale, HCs healthy controls, VAS Visual Analogue Scales; Data presented as mean ± SEM
^#t test

ISSN: 1756-0500