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Table 1 Demographic and clinical data of control (C), HBV infected (HBV), hepatocellular carcinoma (HCC) and HBV-related HCC (HBV + HCC) groups

From: Hepatocyte paraffin 1 and arginase-1 are effective panel of markers in HBV-related HCC diagnosis in fine-needle aspiration specimens

Parameters

C, N(%)

HBV, N(%)

HCC, N(%)

HBV + HCC, N(%)

P

Age (years)

P = 0.161

F = 1.740

 Mean age

33 ± 6.216

53.85 ± 9.582

55.44 ± 10.305

57.13 ± 9.819

 Age range

37–61

31–71

30–72

37–72

Median

Median

Median

Median

51.50 years

58 years

56 years

59 years

Sex

P = 0.738

F = 0.413

 Male

24(80.0)

28(70.0)

32(78.0)

29(72.5)

 Female

6(20.0)

12(30.0)

9(22.0)

11(27.5)

Hepatocellular carcinoma

 Well or moderately differentiated

  

37(90.2)

35(87.5)

 

 Poorly differentiated

-

-

4(9.8)

5(12.5)

HCC grading

 Early

  

39(95.1)

38(95.0)

 

 G1

 

1(2.4)

2(5.0)

 G2–G3

 

1(2.4)

0

Total bilirubin (μ mol/l)

15.43 ± 5.65

18.76 ± 6.75

28.45 ± 12.24

33.10 ± 11.77

 

ALT (U/L)

26.23 ± 10.90

45.76 ± 32.03

88.25 ± 95.32

117.76 ± 102.54

 

AFP (ng/mL)

2.12 ± 1.14

3.12 ± 2.79

421.21 ± 104.33

534.54 ± 420.76

 

Serum HBV DNA level

 Mean, log IU/mL (1SD)

7.6 ± 0.8

7.8 ± 0.1

 

HBs-Ag positive

40(100.0)

40(100.0)

 

HBe-Ab positive

12(30.0)

15(37.5)