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Table 1 Demographic and clinical data of control (C), HBV infected (HBV), hepatocellular carcinoma (HCC) and HBV-related HCC (HBV + HCC) groups

From: Hepatocyte paraffin 1 and arginase-1 are effective panel of markers in HBV-related HCC diagnosis in fine-needle aspiration specimens

Parameters C, N(%) HBV, N(%) HCC, N(%) HBV + HCC, N(%) P
Age (years) P = 0.161
F = 1.740
 Mean age 33 ± 6.216 53.85 ± 9.582 55.44 ± 10.305 57.13 ± 9.819
 Age range 37–61 31–71 30–72 37–72
Median Median Median Median
51.50 years 58 years 56 years 59 years
Sex P = 0.738
F = 0.413
 Male 24(80.0) 28(70.0) 32(78.0) 29(72.5)
 Female 6(20.0) 12(30.0) 9(22.0) 11(27.5)
Hepatocellular carcinoma
 Well or moderately differentiated    37(90.2) 35(87.5)  
 Poorly differentiated - - 4(9.8) 5(12.5)
HCC grading
 Early    39(95.1) 38(95.0)  
 G1   1(2.4) 2(5.0)
 G2–G3   1(2.4) 0
Total bilirubin (μ mol/l) 15.43 ± 5.65 18.76 ± 6.75 28.45 ± 12.24 33.10 ± 11.77  
ALT (U/L) 26.23 ± 10.90 45.76 ± 32.03 88.25 ± 95.32 117.76 ± 102.54  
AFP (ng/mL) 2.12 ± 1.14 3.12 ± 2.79 421.21 ± 104.33 534.54 ± 420.76  
Serum HBV DNA level
 Mean, log IU/mL (1SD) 7.6 ± 0.8 7.8 ± 0.1  
HBs-Ag positive 40(100.0) 40(100.0)  
HBe-Ab positive 12(30.0) 15(37.5)