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Table 3 Diagnostic accuracy for detection of hepatocellular carcinoma using one or two markers

From: Hepatocyte paraffin 1 and arginase-1 are effective panel of markers in HBV-related HCC diagnosis in fine-needle aspiration specimens

  Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy
One marker
 Arg-1 96.3 88.4 95.5 87.5 88.4
 HepPar-1 72.7 84.3 82.2 64.3 77.8
Two markers
 All 2 positive 70.6 100 100 77.6 89.4
 At least 1 positive 84.3 82.4 88.6 85.4 72.2
  1. Arg-1 arginase-1, HepPar-1 hepatocyte paraffin 1, NPV negative predictive value, PPV positive predictive value