Fig. 3
Effect of HS1 mAb administration on STSS clinical isolate-infected mice. C57BL/6 mice (male, 6-week-old) were intraperitoneally inoculated with NIH34 (4 × 107 colony-forming unites per mouse). HS1, HS2, HS3 mAbs, and control mouse IgG (1 mg per mouse) were administrated 1 h a before (n = 11 mice per group) or b after infection (n = 12 mice per group). Mouse survival was monitored for the indicated time period. The combined data from two independent experiments (n = 5 or 6 mice per group) are shown. *p < 0.05 by log-rank test versus control mouse IgG-treated group