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Fig. 3 | BMC Research Notes

Fig. 3

From: Reducing Glut2 throughout the body does not result in cognitive behaviour differences in aged male mice

Fig. 3

Inactivating one allele of Slc2a2 does not affect recognition memory in mice. a Discrimination index (DI) of 2 min novel object recognition (NOR): average results from 2 repeats of the experiment during week 33. Both groups performed the task above the level of chance (DI = 0): Slc2a2+/+ p = 0.0067, t = 3.805, df = 7 and Slc2a2+/− p = 0.004, t = 4.852, df = 12. b Exploration time of each group within the Encoding (E) and Retention/ Retrieval (R/R)t phases of 2 min NOR test: average results from 2 repeats of the experiment. c DI of 24 h NOR: results from 1 experiment during week 37. Neither group performed the task above the level of chance: Slc2a2+/+ p = 0.7869, t = 0.2809, df = 7 and Slc2a2+/− p = 0.8189, t = 0.2340 and df = 12. d Exploration time of each group within the Encoding and Retention/ Retrieval phases of 24 h NOR: average results from 1 test. Significant differences assessed by one-way ANOVA with multiple comparisons; *: p = 0.0338 vs Slc2a2+/+ trial (q = 4.034; df = 38); $$: p = 0.0028 vs Slc2a2+/− trial (q = 5.374; df = 38). E: DI of 2 min object placement test: results from 1 experiment during week 42. Slc2a2+/+ group did not perform the task above the level of chance: p = 0.1698, t = 1.530, df = 7. Slc2a2+/− group did perform the task above the level of chance: p = 0.0028, t = 3.745, df = 12. F: Exploration time of each group within the Encoding and Retention/ Retrieval t phases of 2 min object placement test: results from 1 experiment

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