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Fig. 1 | BMC Research Notes

Fig. 1

From: Voluntary exercise in mesothelioma: effects on tumour growth and treatment response in a murine model

Fig. 1

Peak VE activity occurs between 2200 and 0600 h. a Schematic of experimental design. MexTAg mice (n = 28-30/group, 3 mice per cage) were exposed to asbestos (6 mg total over 2 i.p. injections 4 week apart; black arrows) in the presence or absence of active running wheels (icons) as indicated. b Age distribution (median + range) between experimental and control groups. Age matched (Young: 90 days; Old (25 weeks) 265 days), non-asbestos exposed mice were used as controls to assess the impact of exercise over time in the absence of asbestos exposure. c Actogram depicting VE (active wheel running) over 6 consecutive days. Peak VE activity consistently occurred over an 8 h period between 2200 and 0600 h. Data shown are from a single cage from the Pre-Exp VE group and are representative of all VE groups. Data was collected 24/7 for 70 weeks and data between 2200 and 0600 h used for analysis

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