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Table 1 Changes in age-standardised cancer incidence and mortality rates for people aged under 75 years in Australia over the study period from 1995 to 2015 and the last period identified by Joinpoint analysis (A incidence rate; B mortality rate)

From: Changes in cancer incidence and mortality in Australia over the period 1996–2015

Cancer type

Over the study period from 1995 to 2015

Over the last period identified by Joinpoint

Males

Females

Total

Males

Females

Total

ASR

AAPC (95%CI)

ASR

AAPC (95%CI)

ASR

AAPC (95%CI)

Period

APC (95%CI)

Period

APC (95%CI)

Period

APC (95%CI)

(A) Incidence rate (ranked by the total numbers of cases observed in 2015)

All cancers aged 0–74 years

397.8–392.6

− 0.1 (− 0.4, 0.2)*

309.9–337.3

0.5 (0.4, 0.5)

350.7–364.4

0.2 (0.1, 0.3)

2008–2015

− 1.4 (− 1.6, − 1.3)

2009–2015

0.9 (0.7, 1.0)

2008–2015

− 0.4 (− 0.5, − 0.3)

Aged 15–74 years

 Prostate (C61)

125.5–137.2

0.5 (− 0.9, 1.8)*

  

125.5–137.2

0.5 (− 0.9, 1.8)*

2008–2015

− 4.5 (− 5.2, − 3.7)

  

2008–2015

− 4.5 (− 5.2, − 3.7)

 Breast (C50)

  

128.8–144.6

0.7 (0.4, 0.9)

128.8–144.6

0.7 (0.4, 0.9)

  

2007–2015

1.4 (1.1, 1.7)

2007–2015

1.4 (1.1, 1.7)

 Colon and rectum (C18–C20)

67.4–54.5

− 1.1 (− 1.4, − 0.8)

46.2–39.7

− 0.8 (− 1.4, − 0.2)

56.5–46.9

− 1.0 (− 1.2, − 0.8)

2013–2015

− 0.6 (− 3.0, 1.7)*

2007–2015

− 1.8 (− 2.1, − 1.6)

2008–2015

− 2.2 (− 2.6, − 1.8)

 Melanoma (C43)

53.7–59.9

0.4 (0.2, 0.7)

42.9–45.4

0.2 (− 0.1, 0.5)*

48.2–52.5

0.3 (0.1, 0.6)

2011–2015

0.9 (0.0, 1.9)

2010–2015

1.3 (0.6, 1.9)

2011–2015

1.3 (0.4, 2.2)

 Lung (C33–C34)

61.0–39.7

− 2.1 (− 2.4, − 1.9)

24.6–30.8

1.1 (0.7, 1.5)

42.1–35.2

− 0.9 (− 1.1, − 0.7)

2010–2015

− 1.2 (− 1.5, − 1.0)

2012–2015

1.5 (0.3, 2.8)

2011–2015

− 0.2 (− 0.5, 0.2)*

 Head and neck (C00–C14, C30–C32)

32.9–27.4

− 0.9 (− 1.6, − 0.1)

9.5–8.8

− 0.5 (− 0.9, − 0.1)

21.0–18.0

− 0.8 (− 1.0, − 0.5)

2005–2015

0.1 (− 0.1, 0.4)*

2013–2015

− 2.4 (− 5.8, 1.2)*

2004–2015

0.3 (0.0, 0.6)

 Non-Hodgkin lymphoma (C82–C85)

18.9–20.2

0.4 (− 0.1, 0.9)*

14.1–14.6

0.1 (− 0.3, 0.6)*

16.5–17.4

0.4 (0.3, 0.5)

2012–2015

− 1.7 (− 3.2, − 0.2)

2008–2015

0.7 (0.5, 1.0)

1995–2015

0.4 (0.3, 0.5)

 Kidney (C64)

12.4–18.8

2.0 (0.5, 3.6)

6.2–8.6

1.8 (1.2, 2.5)

9.2–13.6

1.9 (1.8, 2.1)

2010–2015

3.8 (2.3, 5.4)

2013–2015

− 0.6 (− 4.2, 3.1)*

1995–2015

1.9 (1.8, 2.1)

 Leukaemia (C91–C95)

13.2–15.1

0.8 (0.4, 1.1)

8.1–9.1

0.5 (0.2, 0.8)

10.6–12.1

0.7 (0.4, 1.1)

2013–2015

2.7 (0.6, 5.0)

2010–2015

− 0.2 (− 1.1, 0.7)*

2013–2015

2.4 (0.5, 4.2)

 Thyroid (C73)

2.9–7.6

5.1 (4.2, 6.0)

8.6–21.7

4.8 (4.5, 5.1)

5.7–14.7

4.9 (4.6, 5.2)

2013–2015

2.9 (− 1.4, 7.4)*

2013–2015

1.0 (− 0.9, 3.0)*

2013–2015

1.7 (0.2, 3.3)

 Corpus uteri and uterus (C54–C55)

  

16.3–20.8

1.3 (0.9, 1.7)

16.3–20.8

1.3 (0.9, 1.7)

  

2010–2015

0.9 (0.5, 1.3)

2010–2015

0.9 (0.5, 1.3)

 Unknown primary (C77–C80, C97)

14.8–6.4

− 4.2 (− 4.7, − 3.8)

10.5–4.1

− 4.7 (− 5.2, − 4.2)

12.6–5.2

− 4.3 (− 4.7, − 4.0)

2008–2015

− 3.4 (− 4.0, − 2.9)

2013–2015

− 6.9 (− 9.8, − 4.0)

2008–2015

− 3.7 (− 4.1, − 3.3)

 Pancreas (C25)

8.9–10.7

1.0 (0.4, 1.6)

5.8–8.0

1.5 (1.2, 1.8)

7.3–9.3

1.1 (0.9, 1.4)

2012–2015

2.2 (0.6, 3.8)

2007–2015

2.2 (1.6, 2.9)

2001–2015

1.5 (1.4, 1.7)

 Stomach (C16)

12.9–8.8

− 1.9 (− 2.1, − 1.7)

5.3–4.0

− 1.6 (− 1.8, − 1.5)

9.0–6.4

− 1.8 (− 2.0, − 1.6)

2007–2015

− 0.9 (− 1.3, − 0.5)

1995–2015

− 1.6 (− 1.8, − 1.5)

2007–2015

− 1.0 (− 1.4, − 0.7)

 Bladder (C67)

15.2–9.8

− 2.1 (− 2.4, − 1.9)

3.8–2.6

− 1.9 (− 2.9, − 1.0)

9.3–6.1

− 2.0 (− 2.5, − 1.5)

2005–2015

− 0.8 (− 1.1, − 0.5)

2005–2015

− 0.7 (− 1.3, 0.0)*

2004–2015

− 0.8 (− 1.0, − 0.6)

 Brain (C71)

8.4–8.4

0.1 (− 0.6, 0.7)*

5.5–5.1

− 0.3 (− 1.8, 1.2)*

6.9–6.7

− 0.2 (− 0.5, 0.2)*

2013–2015

2.1 (− 1.8, 6.1)*

2001–2015

− 0.7 (− 1.1, − 0.3)

2010–2015

− 1.3 (− 2.6, − 0.1)

 Ovary (C56)

  

13.0–9.5

− 1.5 (− 2.0, − 0.9)

13.0–9.5

− 1.5 (− 2.0, − 0.9)

  

2013–2015

− 4.5 (− 7.9, − 1.1)

2013–2015

− 4.5 (− 7.9, − 1.1)

 Liver (C22)

4.9–11.6

4.5 (4.3, 4.7)

1.4–3.2

4.5 (4.0, 5.1)

3.1–7.3

4.6 (4.5, 4.7)

2003–2015

5.1 (4.8, 5.3)

2004–2015

3.8 (3.1, 4.4)

1995–2015

4.6 (4.5, 4.7)

 Oesophagus (C15)

7.0–6.9

0.2 (− 0.2, 0.5)*

2.7–2.0

− 1.7 (− 2.8, − 0.5)

4.8–4.4

− 0.4 (− 0.9, 0.2)*

2011–2015

− 1.8 (− 3.2, − 0.4)

2009–2015

− 1.2 (− 2.1, − 0.2)

2009–2015

− 1.4 (− 2.0, − 0.9)

 Cervix (C53)

  

13.8–8.8

− 1.9 (− 2.2, − 1.7)

13.8–8.8

− 1.9 (− 2.2, − 1.7)

  

2002–2015

0.5 (0.3, 0.8)

2002–2015

0.5 (0.3, 0.8)

 Testis (C62)

7.6–9.8

1.3 (1.0, 1.6)

  

7.6–9.8

1.3 (1.0, 1.6)

2012–2015

2.0 (0.4, 3.7)

  

2012–2015

2.0 (0.4, 3.7)

 Gallbladder and bile duct (C23–C24)

2.6–2.5

− 0.3 (− 1.0, 0.5)*

2.7–2.4

− 0.7 (− 1.5, 0.0)*

2.7–2.5

− 0.5 (− 1.3, 0.2)*

2013–2015

5.3 (− 0.7, 11.8)*

2008–2015

1.6 (0.9, 2.3)

2009–2015

2.2 (1.4, 3.0)

 Other cancers

33.9–41.9

1.2 (0.9, 1.4)

22.8–33.2

1.8 (1.3, 2.4)

28.3–37.5

1.4 (1.0, 1.8)

2009–2015

1.1 (0.7, 1.5)

2009–2015

1.8 (1.3, 2.2)

2013–2015

0.5 (− 1.4, 2.4)*

All cancers aged 0–14 years

16.0–16.7

0.2 (− 0.5, 0.9)*

13.1–15.6

0.9 (0.6, 1.2)

14.6–16.1

0.6 (− 0.1, 1.2)*

2012–2015

− 2.5 (− 4.4, − 0.5)

2009–2015

2.1 (1.5, 2.7)

2012–2015

− 0.5 (− 2.6, 1.5)*

(B) Mortality rate (ranked by the total numbers of deaths observed in 2015)

All cancers aged 0–74 years

151.1–96.3

− 2.2 (− 2.3, − 2.2)

102.6–72.6

− 1.7 (− 1.8, − 1.7)

125.6–84.3

− 2.0 (− 2.0, − 1.9)

2001–2015

− 2.1 (− 2.2, − 2.1)

1999–2015

− 1.6 (− 1.7, − 1.6)

2000–2015

− 1.9 (− 1.9, − 1.9)

Aged 15–74 years

 Lung (C33–C34)

51.5–26.3

− 3.2 (− 3.3, − 3.2)

19.4–18.0

− 0.3 (− 0.6, − 0.1)

34.8–22.1

− 2.2 (− 2.4, − 2.1)

2002–2015

− 2.9 (− 3.0, − 2.8)

2011–2015

− 1.4 (− 2.8, 0.0)*

2011–2015

− 2.3 (− 2.9, − 1.8)

 Colon and rectum (C18–C20, C26.0)

26.8–14.0

− 3.2 (− 3.5, − 3.0)

17.1–9.3

− 3.2 (− 3.4, − 3.0)

21.8–11.6

− 3.2 (− 3.3, − 3.1)

2006–2015

− 3.5 (− 3.7, − 3.3)

1995–2015

− 3.2 (− 3.4, − 3.0)

1995–2015

− 3.2 (− 3.3, − 3.1)

 Breast (C50)

  

28.6–17.2

− 2.5 (− 2.9, − 2.1)

28.6–17.2

− 2.5 (− 2.9, − 2.1)

  

2003–2015

− 2.4 (− 2.6, − 2.2)

2003–2015

− 2.4 (− 2.6, − 2.2)

 Unknown primary (C77–C80, C97)

10.9–5.9

− 3.2 (− 4.2, − 2.3)

7.4–4.0

− 3.3 (− 3.9, − 2.6)

9.1–4.9

− 3.2 (− 3.9, − 2.5)

2005–2015

− 5.9 (− 6.4, − 5.4)

2006–2015

− 5.9 (− 6.4, − 5.5)

2005–2015

− 5.7 (− 6.1, − 5.3)

 Pancreas (C25)

8.1–7.9

− 0.2 (− 0.5, 0.2)*

5.2–5.5

0.3 (− 0.9, 1.5)*

6.6–6.7

0.1 (0.0, 0.3)*

2007–2015

− 0.8 (− 1.2, − 0.4)

2004–2015

− 0.3 (− 0.7, 0.1)*

2006–2015

− 0.4 (− 0.7, − 0.2)

 Brain (C71)

7.2–6.5

− 0.6 (− 1.3, 0.1)*

4.7–3.9

− 0.9 (− 1.5, − 0.2)

5.9–5.2

− 0.7 (− 1.1, − 0.3)

2005–2015

0.1 (− 0.3, 0.4)*

2006–2015

0.3 (− 0.1, 0.8)*

2006–2015

0.3 (0.0, 0.5)*

 Prostate (C61)

15.3–7.9

− 3.4 (− 3.7, − 3.1)

  

15.3–7.9

− 3.4 (− 3.7, − 3.1)

2004–2015

− 3.8 (− 4.1, − 3.5)

  

2004–2015

− 3.8 (− 4.1, − 3.5)

 Melanoma (C43)

6.6–5.0

− 1.1 (− 1.7, − 0.6)

3.2–2.5

− 1.1 (− 2.1, − 0.2)

4.9–3.7

− 1.1 (− 1.5, − 0.7)

2012–2015

− 8.0 (− 11.2, − 4.7)

2008–2015

− 2.6 (− 4.0, − 1.1)

2012–2015

− 6.9 (− 9.6, − 4.0)

 Non-Hodgkin lymphoma (C82–C85)

7.7–4.0

− 3.3 (− 3.7, − 2.9)

5.4–2.1

− 4.6 (− 5.0, − 4.1)

6.5–3.0

− 3.8 (− 4.1, − 3.5)

2007–2015

− 2.6 (− 3.2, − 2.0)

2008–2015

− 2.2 (− 3.0, − 1.4)

2008–2015

− 2.3 (− 2.8, − 1.9)

 Leukaemia (C91–C95)

6.8–4.3

− 2.2 (− 2.5, − 1.9)

3.9–2.8

− 1.5 (− 1.7, − 1.2)

5.3–3.6

− 1.9 (− 2.4, − 1.5)

2001–2015

− 2.6 (− 2.9, − 2.3)

2008–2015

− 0.6 (− 1.0, − 0.1)

2005–2015

− 2.1 (− 2.4, − 1.8)

 Liver (C22)

4.3–7.7

2.6 (2.2, 3.0)

1.7–2.9

3.3 (2.9, 3.6)

3.0–5.3

2.9 (2.6, 3.1)

2010–2015

2.7 (1.9, 3.5)

1995–2015

3.3 (2.9, 3.6)

2003–2015

3.5 (3.3, 3.7)

 Head and neck (C00–C14, C30–C32)

9.0–5.2

− 2.7 (− 3.0, − 2.3)

2.0–1.4

− 1.7 (− 3.0, − 0.4)

5.4–3.3

− 2.5 (− 3.1, − 1.9)

2007–2015

− 1.1 (− 1.8, − 0.4)

2006–2015

0.2 (− 0.7, 1.1)*

2006–2015

− 0.9 (− 1.4, − 0.5)

 Oesophagus (C15)

6.5–5.6

− 0.8 (− 1.4, − 0.2)

2.0–1.3

− 2.1 (− 2.4, − 1.8)

4.2–3.4

− 1.1 (− 1.6, − 0.6)

2004–2015

− 1.5 (− 1.8, − 1.2)

1995–2015

− 2.1 (− 2.4, − 1.8)

2004–2015

− 1.7 (− 2.0, − 1.3)

 Stomach (C16)

7.7–3.8

− 3.5 (− 4.1, − 2.9)

3.3–2.0

− 2.8 (− 3.1, − 2.4)

5.4–2.8

− 3.2 (− 3.9, − 2.5)

2013–2015

− 6.9 (− 11.8, − 1.7)

1995–2015

− 2.8 (− 3.1, − 2.4)

2013–2015

− 5.2 (− 10.6, 0.6)*

 Ovary (C56)

  

7.7–5.0

− 2.1 (− 2.8, − 1.3)

7.7–5.0

− 2.1 (− 2.8, − 1.3)

  

2013–2015

− 5.0 (− 9.7, − 0.1)

2013–2015

− 5.0 (− 9.7, − 0.1)

 Kidney (C64)

4.7–3.3

− 1.7 (− 1.9, − 1.5)

2.5–1.3

− 3.2 (− 4.1, − 2.3)

3.6–2.3

− 2.1 (− 2.2, − 2.0)

1995–2015

− 1.7 (− 1.9, − 1.5)

2001–2015

− 3.5 (− 3.8, − 3.1)

1995–2015

− 2.1 (− 2.2, − 2.0)

 Bladder (C67)

3.8–2.1

− 3.2 (− 3.9, − 2.5)

1.2–0.7

− 2.7 (− 3.1, − 2.3)

2.5–1.4

− 3.0 (− 3.7, − 2.4)

2011–2015

− 6.5 (− 9.7, − 3.1)

1995–2015

− 2.7 (− 3.1, − 2.3)

2011–2015

− 5.8 (− 8.9, − 2.7)

 Corpus uteri and uterus (C54–C55)

  

2.2–2.5

0.6 (− 0.4, 1.7)*

2.2–2.5

0.6 (− 0.4, 1.7)*

  

2010–2015

4.0 (2.6, 5.4)

2010–2015

4.0 (2.6, 5.4)

 Cervix (C53)

  

3.8–1.9

− 3.5 (− 4.5, − 2.4)

3.8–1.9

− 3.5 (− 4.5, − 2.4)

  

2004–2015

− 0.3 (− 0.7, 0.2)*

2004–2015

− 0.3 (− 0.7, 0.2)*

 Gallbladder and bile duct (C23–C24)

1.0–0.5

− 4.0 (− 5.9, − 2.1)

1.5–0.6

− 5.6 (− 6.2, − 5.1)

1.3–0.5

− 4.8 (− 7.1, − 2.5)

2005–2015

− 1.0 (− 2.4, 0.4)*

1995–2015

− 5.6 (− 6.2, − 5.1)

2005–2015

− 3.4 (− 5.0, − 1.7)

 Thyroid (C73)

0.3–0.3

1.0 (− 1.2, 3.4)*

0.3–0.4

0.4 (− 3.8, 4.9)*

0.3–0.3

0.8 (− 1.2, 2.8)*

1997–2015

− 0.5 (− 1.1, 0.1)*

2004–2015

1.3 (− 0.3, 2.8)*

2004–2015

0.5 (− 0.2, 1.1)*

 Testis (C62)

0.4–0.2

− 3.4 (− 4.3, − 2.4)

  

0.4–0.2

− 3.4 (− 4.3, − 2.4)

2002–2015

− 0.9 (− 2.1, 0.3)*

  

2002–2015

− 0.9 (− 2.1, 0.3)*

 Other cancers

13.2–12.1

− 0.4 (− 0.8, 0.0)*

7.3–7.0

− 0.2 (− 0.8, 0.4)*

10.1–9.5

− 0.3 (− 0.7, 0.1)*

2005–2015

− 0.3 (− 0.5, 0.0)

2007–2015

− 0.8 (− 1.1, − 0.5)

2004–2015

− 0.2 (− 0.4, − 0.1)

All cancers aged 0–14 years

4.5–2.3

− 3.6 (− 4.5, − 2.7)

3.1–1.6

− 2.9 (− 3.4, − 2.5)

3.8–2.0

− 3.2 (− 3.9, − 2.5)

2007–2015

− 1.0 (− 3.2, 1.2)*

1995–2015

− 2.9 (− 3.4, − 2.5)

2008–2015

− 1.1 (− 3.1, 0.9)*

  1. All cancers combined: ICD-10 codes C00–C97, D45, D46, D47.1, D47.3–D47.5. C26.0 (“malignant neoplasms of the intestinal tract unspecified”) was included in colorectal cancer mortality, as it has been reported that deaths certified as ‘bowel cancer’ tended to be coded to C26.0 [7]
  2. ASR age-standardised rate. All rates were age-standardised to the Australian 2001 population, AAPC average annual percent change over the whole study period from 1995 to 2015, APC annual percent change, CI confidence interval
  3. *Change not statistically significant (p value ≥ 0.05) for the Joinpoint analysis of changes in rates