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Table 2 Clinical presentation of patients with OROV

From: Oropouche infection a neglected arbovirus in patients with acute febrile illness from the Peruvian coast

 

Total, n = 496 (%)

OROV, n = 131 (%)

Co-infections

OROV, n = 82 (%)

OROV/DENV, n = 36 (%)

OROV/ZIKV, n = 9 (%)

OROV/CHIKV, n = 1 (%)

Others*, N = 3 (%)

Clinical symptoms

 Headache

444 (89.5)

112 (85.5)

71 (86.6)

29 (80.6)

8 (88.9)

1 (100.0)

3 (100.0)

 Myalgia

419 (84.5)

106 (80.9)

66 (80.5)

27 (75.0)

9 (100.0)

1 (100.0)

3 (100.0)

 Arthralgia

396 (79.8)

95 (72.5)

57 (69.5)

28 (77.8)

7 (77.8)

1 (100.0)

2 (66.6)

 Retroocular pain

337 (67.9)

70 (53.4)

44 (53.7)

17 (47.2)

6 (66.7)

1 (100.0)

2 (66.6)

 Hyporexia

312 (62.9)

89 (67.9)

57 (69.5)

21 (58.3)

7 (77.8)

1 (100.0)

3 (100.0)

 Low back pain

270 (54.4)

66 (50.4)

37 (45.1)

19 (52.8)

7 (77.8)

1 (100.0)

2 (66.6)

 Nausea/Vomiting

251 (50.6)

62 (47.3)

40 (48.8)

15 (41.7)

5 (55.6)

0 (0.0)

2 (66.6)

 Odynophagia

184 (37.1)

48 (36.6)

33 (40.2)

11 (30.6)

3 (33.3)

0 (0.0)

1 (33.3)

 Acne

89 (17.9)

25 (19.1)

15 (18.3)

7 (19.4)

3 (33.3)

0 (0.0)

0 (0.0)

 Shaking chills

3 (0.6)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Conjuntival injection

3 (0.6)

1 (0.8)

0 (0.0)

1 (2.8)

0 (0.0)

0 (0.0)

0 (0.0)

 Dizziness

1 (0.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Cough

1 (0.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Bleeding manifestations

 Petechiae

11 (2.2)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Epistaxis

9 (1.8)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Gingivorrhagia

3 (0.6)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Ecchymosis

2 (0.4)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Mane

2 (0.4)

2 (1.5)

2 (2.4)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Gynecrosis

1 (0.2)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Hemoptoic sputum

1 (0.2)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Alarm signals

 Intense and continuous abdominal pain

22 (4.4)

4 (3.1)

4 (4.9)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Platelet Decrease

7 (1.4)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Persistent vomiting

6 (1.2)

3 (2.3)

2 (2.4)

1 (2.6)

0 (0.0)

0 (0.0)

0 (0.0)

 Hematocrit Increase

6 (1.2)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Chest pain or dyspnea

5 (1.0)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Sudden decrease in T° or hypothermia

3 (0.6)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Excessive decay or lipotimia

3 (0.6)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Altered mental state (drowsiness)

1 (0.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Hepatomegaly or jaundice

1 (0.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Crash signs

 Cold or cyanotic limbs

2 (0.4)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Arterial hypotension

1 (0.2)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 Fast and weak pulse

1 (0.2)

1 (0.8)

1 (1.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

 BP differential < 20 MMHg

1 (0.2)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)