Fig. 1From: Inhibition of Ref(2)P, the Drosophila homologue of the p62/SQSTM1 gene, increases lifespan and leads to a decline in motor functionAltered expression of Ref(2)P directed through the D42-Gal4 transgene affects longevity and climbing ability. a Longevity assay of Drosophila melanogaster males displaying altered Ref(2)P expression in the motor neurons. Longevity is depicted by percent survival. Significance is P < 0.05 using the log-rank test with Bonferroni correction. Error bars represent standard error of the mean. b Locomotor assay of D. melanogaster males displaying altered Ref(2)P expression in the motor neurons. Climbing ability was determined by a nonlinear curve fit (CI = 95%). Error bars indicate standard error of the meanBack to article page