Fig. 1

a Experimental timeline, a group of mice (n = 4) was chemically sympathectomized with 2 doses of 6-OHDA i.p., the control group (n = 5) received saline i.p., 14 days after sympathectomy, L5178Y-R cells were inoculated in the right flank of control and sympathectomized animals. After mice euthanasia, tissues were surgically excised and stored at − 80 ºC until analysis (b) tumor volume progression (c) interscapular and inguinal fat wet weight (d) Relative gene expression of Th was calculated by the 2^−ΔΔCT method. Data represent the mean ± SEM of 4–5 animals from a representative experiment. Resulting values were analyzed with the Student t test p < 0.05