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Table 3 Association of the the IFN-Ɣ + 874 A/T genotypes with clinical parameters of BC

From: The IFN-Ɣ + 874 A/T polymorphism is associated with malignant breast cancer in a population from the southwest of Iran

 

AA

1.0-ref

AT

OR for ATvsAA (95% CI)

p-value

A

1.0-ref

T

OR for TvsA (95% CI)

p-value

Malignancy

3 (6.5)

44 (93.5)

5.3 (1.1–26)

0.05

50 (53.2)

44 (46.8)

1.5 (0.7–3)

0.3

Benign

11 (27)

30 (73)

  

52 (62.5)

30 (37.5)

  

Metastasis

10 (13.5)

64 (68.5)

1.7 (0.4–7.4)

0.4

84 (56.8)

64 (43.2)

1.2 (0.5–2.7)

0.7

No metastasis

3 (21.4)

11 (78.6)

  

17 (60.7)

11 (39.3)

  

Right

7 (17.1)

34 (82.9)

0.7 (0.2–2.7)

0.6

48 (58.5)

34 (41.5)

1.1 (0.6–2)

0.8

Left

6 (13)

40 (87)

  

52 (56.5)

40 (43.5)

  

HER 2 positive

6 (11.3)

47 (88.7)

2.3 (0.6–8.5)

0.2

59 (55.7)

47 (44.3)

0.8 (0.4–1.6)

0.5

HER 2 negative

5 (22.7)

17 (77.3)

  

27 (61.4)

17 (38.6)

  

PR positive

8 (14.3)

48 (85.7)

1.1 (0.3–4.8)

0.87

64 (57.1)

48 (42.9)

0.97 (0.5–2)

0.9

PR negative

3 (15.8)

16 (84.2)

  

22 (57.9)

16 (42.1)

  

ER positive

8 (13.3)

52 (86.7)

1.6 (0.4–7)

0.5

68 (56.7)

52 (43.3)

0.87 (0.4–1.97)

0.7

ER negative

3 (20)

12 (80)

  

18 (60)

12 (40)

  
  1. Data are expressed as number (%)