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Table 3 Association of the the IFN-Ɣ + 874 A/T genotypes with clinical parameters of BC

From: The IFN-Ɣ + 874 A/T polymorphism is associated with malignant breast cancer in a population from the southwest of Iran

  AA
1.0-ref
AT OR for ATvsAA (95% CI) p-value A
1.0-ref
T OR for TvsA (95% CI) p-value
Malignancy 3 (6.5) 44 (93.5) 5.3 (1.1–26) 0.05 50 (53.2) 44 (46.8) 1.5 (0.7–3) 0.3
Benign 11 (27) 30 (73)    52 (62.5) 30 (37.5)   
Metastasis 10 (13.5) 64 (68.5) 1.7 (0.4–7.4) 0.4 84 (56.8) 64 (43.2) 1.2 (0.5–2.7) 0.7
No metastasis 3 (21.4) 11 (78.6)    17 (60.7) 11 (39.3)   
Right 7 (17.1) 34 (82.9) 0.7 (0.2–2.7) 0.6 48 (58.5) 34 (41.5) 1.1 (0.6–2) 0.8
Left 6 (13) 40 (87)    52 (56.5) 40 (43.5)   
HER 2 positive 6 (11.3) 47 (88.7) 2.3 (0.6–8.5) 0.2 59 (55.7) 47 (44.3) 0.8 (0.4–1.6) 0.5
HER 2 negative 5 (22.7) 17 (77.3)    27 (61.4) 17 (38.6)   
PR positive 8 (14.3) 48 (85.7) 1.1 (0.3–4.8) 0.87 64 (57.1) 48 (42.9) 0.97 (0.5–2) 0.9
PR negative 3 (15.8) 16 (84.2)    22 (57.9) 16 (42.1)   
ER positive 8 (13.3) 52 (86.7) 1.6 (0.4–7) 0.5 68 (56.7) 52 (43.3) 0.87 (0.4–1.97) 0.7
ER negative 3 (20) 12 (80)    18 (60) 12 (40)   
  1. Data are expressed as number (%)