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Table 1 Mean sizes of CL lesions (mm) in BALB/c mice before and during the treatment with F.carica latex gel

From: Effects of topical gel formulation of Ficus carica latex on cutaneous leishmaniasis induced by Leishmania major in BALB/c mice

Group of mice under treatment

Before treatment

First week

Second week

Third week

p-value

Positive control

6.57ā€‰Ā±ā€‰0.85

6.31ā€‰Ā±ā€‰0.69

6.3ā€‰Ā±ā€‰0.78

6.28ā€‰Ā±ā€‰1.05

0.073

Negative control

7.74ā€‰Ā±ā€‰1.07

7.86ā€‰Ā±ā€‰0.93

8.12ā€‰Ā±ā€‰1.2

8.27ā€‰Ā±ā€‰1.16

0.125

Test (once daily)

6.5ā€‰Ā±ā€‰1.08

6.6ā€‰Ā±ā€‰1.41

6.37ā€‰Ā±ā€‰1.28

6.45ā€‰Ā±ā€‰1.33

0.152

Test (twice daily)

5.73ā€‰Ā±ā€‰0.81

6.1ā€‰Ā±ā€‰1.36

6.3ā€‰Ā±ā€‰2.16

6.35ā€‰Ā±ā€‰2.56

0.168

Test (every other day)

6.8ā€‰Ā±ā€‰0.35

6.79ā€‰Ā±ā€‰0.38

6.78ā€‰Ā±ā€‰0.84

6.79ā€‰Ā±ā€‰1.13

0.085

  1. All data are presented in meanā€‰Ā±ā€‰SD