The effect of Melissa officinalis syrup on patients with mild to moderate psoriasis: a randomized, double-blind placebo-controlled clinical trial

Table 2 Results of itch score, PASI score, and DLQI questionnaire between intervention and control groups

Variables	Intervention group (n = 47)	Placebo group (n = 48)	P-value^a
Variables	Mean ± SD	Mean ± SD
Itch
Pre-treatment	6.34 ± 2.68	5.45 ± 2.55	0.104
Post-treatment	3.45 ± 2.18	5.56 ± 2.81	< 0.001
p-value^b	< 0.001	0.886
PASI
Pre-treatment	3.26 ± 3.58	2.95 ± 2.16	0.603
Post-treatment	1.65 ± 2.17	3.36 ± 2.38	< 0.001
p-value	< 0.001	0.002
DLQI
Pre-treatment	67.63 ± 22.97	64.43 ± 23.66	0.503
Post-treatment	74.37 ± 23.89	65.29 ± 23.74	0.065
p-value	0.029	0.519

DLQI dermatology life quality index, PASI psoriasis area and severity index, SD standard deviation
^aP-value is calculated by the independent t-test
^bP-value is calculated by the Paired t-test

ISSN: 1756-0500