Table 1 Inclusion and exclusion criteria
People were considered as eligible if they meet all of the following criteria | People did not enter the trial if they meet one or more of the following criteria | Participants were excluded during the trial if they meet one or more of the following criteria |
|---|---|---|
BMI greater than or equal to 18.5 kg/m2 | A history or current diagnosis of kidney, liver or thyroid disorders, heart diseases, diabetes, different malignancies and other inflammatory comorbidities | Allergic reaction to W-3 or nanocurcumin supplements |
Males and females 20–50 years of age | Low BMI (less than 18.5 kg/m2) | Lack of patient's cooperation |
Episodic migraine | Dietary supplementation during the preceding three months | Pregnancy during the study period |
Stable diet, physical activity or supplements during the trial | Pregnancy, lactation | Self-reported changes in diet and lifestyle |
willingness to participate | Menopause | Changes in dosage or type of routine medications |
| Â | Alcohol or drug abuse and cigarette smoking during the preceding six months | Over 2Â weeks anti-inflammatory drugs consumption |
|  |  | Compliance rate less than 90% |