Risk factors | n (%) | Duration of therapy ≤ 6 months n (%) | Duration of therapy > 6 months n (%) | p value |
---|---|---|---|---|
Gender | 1.000* | |||
Male | 35 (70.0) | 26 (68.4) | 9 (75.0) | |
Female | 15 (30.0) | 12 (31.6) | 3 (25.0) | |
Age group, years (N) | – | |||
≤ 29 | 9 (18.0) | 9 (23.7) | 0 (0) | |
1 | 8 (16.0) | 6 (15.8) | 2 (16.7) | |
40–49 | 13 (26.0) | 11 (28.9) | 2 (16.7) | |
50–59 | 12 (24.0) | 7 (18.4) | 5 (41.7) | |
≥ 60 | 8 (16.0) | 5 (13.2) | 3 (25.0) | |
Education (N) | – | |||
Primary school | 4 (8.0) | 3 (7.9) | 1 (8.3) | |
Junior high school | 7 (14.0) | 5 (13.2) | 2 (16.7) | |
Senior high school | 37 (74.0) | 28 (73.7) | 9 (75.0) | |
Diploma/bachelor degree | 2 (4.0) | 2 (5.3) | 0 (0) | |
Occupation (N) | – | |||
Students/university students | 4 (8.0) | 4 (10.5) | 0 (0) | |
Employed | 27 (54.0) | 21 (55.3) | 6 (50.0) | |
Unemployed | 19 (38.0) | 13 (34.3) | 6 (50.0) | |
Smoking status (N) | 0.125# | |||
No | 34 (68.0) | 28 (73.7) | 6 (50.0) | |
Yes | 16 (32.0) | 10 (26.3) | 6 (50.0) | |
Alcohol consumption | 0.621* | |||
No | 44 (88.0) | 34 (89.5) | 10 (83.3) | |
Yes | 6 (12.0) | 4 (10.5) | 2 (16.7) | |
Genotype ABCB1 rs1045642 | 0.668* | |||
CC | 9 (18.0) | 6 (15.8) | 3 (25.0) | |
CT + TT | 41 (82.0) | 32 (84.2) | 9 (75.0) | |
Genotype ABCB1 rs1128503 | 0.386* | |||
CC | 8 (16.0) | 7 (30.4) | 1 (11.1) | |
CT + TT | 25 (50.0) | 16 (69.6) | 8 (88.9) | |
Missing | 17 (34.0) | – | – | |
Genotype CYP2E1 rs3813867 | – | |||
CC | 50 (100) | 12 (24) | 38 (76) | – |
CT + TT | 0 (0) | – | – |