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Table 1 Correlation of sociodemographic characteristics with duration of therapy (n = 50)

From: Genetic variation of ABCB1 (rs1128503, rs1045642) and CYP2E1 rs3813867 with the duration of tuberculosis therapy: a pilot study among tuberculosis patients in Indonesia

Risk factors

n (%)

Duration of therapy ≤ 6 months

n (%)

Duration of therapy > 6 months

n (%)

p value

Gender

1.000*

 Male

35 (70.0)

26 (68.4)

9 (75.0)

 

 Female

15 (30.0)

12 (31.6)

3 (25.0)

 

Age group, years (N)

 ≤ 29

9 (18.0)

9 (23.7)

0 (0)

 

 1

8 (16.0)

6 (15.8)

2 (16.7)

 

 40–49

13 (26.0)

11 (28.9)

2 (16.7)

 

 50–59

12 (24.0)

7 (18.4)

5 (41.7)

 

 ≥ 60

8 (16.0)

5 (13.2)

3 (25.0)

 

Education (N)

 Primary school

4 (8.0)

3 (7.9)

1 (8.3)

 

 Junior high school

7 (14.0)

5 (13.2)

2 (16.7)

 

 Senior high school

37 (74.0)

28 (73.7)

9 (75.0)

 

 Diploma/bachelor degree

2 (4.0)

2 (5.3)

0 (0)

 

Occupation (N)

 Students/university students

4 (8.0)

4 (10.5)

0 (0)

 

 Employed

27 (54.0)

21 (55.3)

6 (50.0)

 

 Unemployed

19 (38.0)

13 (34.3)

6 (50.0)

 

Smoking status (N)

0.125#

 No

34 (68.0)

28 (73.7)

6 (50.0)

 

 Yes

16 (32.0)

10 (26.3)

6 (50.0)

 

Alcohol consumption

0.621*

 No

44 (88.0)

34 (89.5)

10 (83.3)

 

 Yes

6 (12.0)

4 (10.5)

2 (16.7)

 

Genotype ABCB1 rs1045642

0.668*

 CC

9 (18.0)

6 (15.8)

3 (25.0)

 

 CT + TT

41 (82.0)

32 (84.2)

9 (75.0)

 

Genotype ABCB1 rs1128503

0.386*

 CC

8 (16.0)

7 (30.4)

1 (11.1)

 

 CT + TT

25 (50.0)

16 (69.6)

8 (88.9)

 

 Missing

17 (34.0)

 

Genotype CYP2E1 rs3813867

 CC

50 (100)

12 (24)

38 (76)

 CT + TT

0 (0)

 
  1. Statistical comparisons were performed using #Chi-square test and *Fisher exact test