Fig. 2

Close up comparisons of expression patterns. A, B Schematics of upper (A) and lower (B) molars with buccal side to the left, lingual side to the right. C–G Schematics of stage 3 hair follicle (C), palate (D) eyelid (E), eye (F), and retina (G). H–PP) Expression patterns of Shh (H–N), Gli1 (O–U), Ptch1 (V–BB), Ptch2 (CC–II), and Hhip (JJ–PP) in each structure. See abbreviations list for descriptions. White asterisks indicate histological artifacts where tissues are lacking. The asterisks for the eye structures also indicate the pigmentation of the RPE and is not mRNA staining. Black arrowheads in LL point to Hhip in the condensing mesenchyme surrounding the follicle. White arrows in eyelid panels point to the eyelid signaling field, and the arrowhead denotes a hair follicle. White dashed lines in eye panels denote the iris stroma (below line). White dashed lines in retina panels denote the RPE (below lines) and extraocular mesenchyme including the condensing scleral mesenchyme (above lines)