Table 1 Summary of patient demographics
Preoperative characteristics | Paracetamol (N = 12) | Saline (N = 12) |
|---|---|---|
Age (years) | 56.9 (8.5) | 59.0 (7.0) |
Male gender | 5 (42%) | 9 (75%) |
Weight (kg) | 83.5 (36.8) | 96.1 (41.3) |
Height (cm) | 167.8 ± 9.3 | 171.3 ± 10.2 |
Body mass index (kg/m2) | 21.6 (11.3) | 23.2 (10.4) |
Model for End-stage Liver Disease Score | 20.1 (6.8) | 14.9 (4.7) |
Indication for liver transplant | Paracetamol (N = 12) | Saline (N = 12) |
|---|---|---|
Hepatitis C | 1 (8%) | 4 (33%) |
Hepatitis C + Hepatocellular carcinoma | 5 (42%) | 3 (25%) |
Hepatitis B | 0 (0%) | 2 (17%) |
Hepatitis B + Hepatocellular carcinoma | 1 (8%) | 0 (0%) |
Primary sclerosing cholangitis | 2 (17%) | 1 (8%) |
Non-cirrhotic portal hypertension | 2 (17%) | 1 (8%) |
Alcohol induced liver failure | 1 (8%) | 0 (0%) |
Non-alcoholic steatohepatitis | 0 (0%) | 1 (8%) |
Intraoperative variables | Paracetamol (N = 12) | Saline (N = 12) | P-value |
|---|---|---|---|
Surgery duration (mins) | 475.7 (105.0) | 446.5 (47.9) | 0.4 |
Intraoperative fluid (mL) | 6387 (3273) | 6234 (2771) | 1.0 |
Intraoperative noradrenaline (µg) | 1775 (1932) | 1868 (1407) | 0.7 |