Table 1 Forty-one CpGs and their intraclass correlation coefficients (ICC) using 1) duplicated samples both measured using Qiagen targeted methyl panel, 2) replicated samples measured using Qiagen targeted methylated panel and Illumina HM450K assay

cg18072778^*

1

148,203,924

0.54 (0–0.90)

0.37 (0–0.94)

0.85 (0.54–0.96)

0 (0–0.39)

0.4 (0–0.88)

0.76 (0.56–0.88)

cg04546999^*

1

152,956,430

0.19 (0–0.75)

0.80 (0–0.99)

0.92 (0.74–0.98)

0.09 (0–0.47)

0 (0–0.68)

0.8 (0.63–0.9)

cg17714793

1

153,538,431

0 (0–0.63)

0.99 (0.47–1)

0.72 (0.24–0.92)

cg01608070

1

157,853,274

0.98 (0.89–1)

0.46 (0–0.96)

0.96 (0.84–0.99)

cg21501207

1

162,383,000

0.89 (0.56–0.98)

0.28 (0–0.94)

0.80 (0.43–0.94)

cg26237810

1

200,669,215

0.52 (0–0.89)

0.96 (0–1)

0.78 (0.29–0.95)

cg26354017^*

1

205,819,088

0.92 (0.64–0.98)

0.70 (0–0.97)

0.94 (0.78–0.98)

0.83 (0.67–0.92)

0.46 (0–0.86)

0.83 (0.69–0.92)

cg14159672^*

1

205,819,179

0.95 (0.71–0.99)

0.96 (0.27–1)

0.98 (0.94–1.00)

0.79 (0.57–0.9)

0.76 (0.16–0.95)

0.82 (0.66–0.91)

cg14893161^*

1

205,819,252

0.92 (0.63–0.98)

0.99 (0.59–1)

0.97 (0.89–0.99)

0.94 (0.86–0.97)

0.73 (0–0.94)

0.93 (0.86–0.96)

cg05841700

1

205,819,384

0.96 (0.80–0.99)

0.68 (0–0.98)

0.96 (0.88–0.99)

cg24503407^*

1

205,819,493

0.92 (0.65–0.98)

0 (0–0.96)

0.95 (0.82–0.99)

0.87 (0.74–0.94)

0.8 (0.02–0.98)

0.88 (0.76–0.94)

cg16334093

1

205,819,601

0.87 (0.43–0.97)

0.64 (0–0.97)

0.87 (0.54–0.97)

cg07157834^*

1

205,819,610

0.90 (0.47–0.98)

0 (0–0.89)

0.94 (0.75–0.98)

0.6 (0.29–0.81)

0.26 (0–0.82)

0.65 (0.39–0.81)

cg20004147

2

65,718,931

0.98 (0.92–1)

0.98 (0.47–1)

0.98 (0.94–1.00)

cg21824770

2

243,012,164

0.28 (0–0.78)

0 (0–0.95)

0.88 (0.58–0.97)

cg10123377

3

42,387,525

0.97 (0.87–0.99)

0.68 (0–0.97)

0.92 (0.72–0.98)

cg01760119

3

101,661,383

0.12 (0–0.7)

0.87 (0–0.99)

0.98 (0.93–1.00)

cg12012426^†

4

1,366,464

–

–

–

–

–

–

cg19704288^*

4

1,582,182

0.24 (0–0.79)

0.76 (0–0.98)

0.81 (0.43–0.95)

0 (0–0.38)

0.81 (0.33–0.96)

0.82 (0.66–0.91)

cg02722613^{*, #}

4

25,162,899

0.75 (0.18–0.94)

0 (0–0.89)

0.77 (0.38–0.93)

0.87 (0.71–0.94)

–

–

cg19182683

4

183,730,519

0.98 (0.91–1)

0.94 (0–1)

0.97 (0.89–0.99)

cg07158503^{*, #}

5

135,415,693

0.63 (0–0.92)

0.96 (0.12–1)

0.79 (0.35–0.94)

0.55 (0.22–0.77)

–

–

cg11608150^*

5

135,415,949

0.71 (0.02–0.93)

0.17 (0–0.97)

0.61 (0.03–0.89)

0.91 (0.81–0.96)

0.44 (0–0.94)

0.84 (0.7–0.92)

cg06478886^*

5

135,416,030

0.79 (0.24–0.96)

0.98 (0.44–1)

0.85 (0.54–0.96)

0.94 (0.86–0.97)

0.31 (0–0.83)

0.9 (0.8–0.95)

cg04481923^*

5

135,416,206

0.74 (0.05–0.95)

0 (0–0.89)

0.23 (0–0.71)

0.59 (0.28–0.78)

0.74 (0.04–0.95)

0.62 (0.34–0.79)

cg06536614^*

5

135,416,381

0.81 (0.24–0.95)

0.47 (0–0.95)

0.63 (0.08–0.88)

0.71 (0.46–0.86)

0 (0–0.68)

0.7 (0.47–0.84)

cg25340688^*

5

135,416,398

0.79 (0.21–0.96)

0.99 (0.66–1)

0.85 (0.47–0.95)

0.65 (0.36–0.83)

0.50 (0–0.88)

0.7 (0.47–0.84)

cg26896946^*

5

135,416,405

0.82 (0.29–0.97)

0.55 (0–0.96)

0.76 (0.29–0.93)

0.68 (0.4–0.84)

0.31 (0–0.81)

0.72 (0.53–0.85)

cg00124993^*

5

135,416,412

0.82 (0.21–0.96)

0.96 (0.13–1)

0.87 (0.55–0.97)

0.71 (0.45–0.86)

0.64 (0–0.92)

0.73 (0.52–0.86)

cg18797653^*

5

135,416,613

0.89 (0.54–0.97)

0 (0–0.87)

0.89 (0.59–0.97)

0.50 (0.14–0.74)

0.76 (0.14–0.95)

0.56 (0.25–0.75)

cg09483595^*

5

158,878,381

0.98 (0.91–1)

0.71 (0–0.98)

0.92 (0.68–0.98)

0 (0–0.4)

0.61 (0–0.91)

0.94 (0.88–0.97)

cg13373914

7

67,323,067

0.12 (0–0.74)

1.00 (0.94–1)

0.90 (0.63–0.98)

cg05141217

8

28,491,379

0.96 (0.80–0.99)

1.00 (0.9–1)

0.97 (0.87–0.99)

cg26708920

10

13,826,318

0.94 (0.72–0.99)

0.96 (0.01–1)

0.96 (0.86–0.99)

cg20054939^*

12

133,614,314

0.66 (0–0.92)

0 (0–0)

0.08 (0–0.63)

0 (0–0.41)

0 (0–0.72)

0 (0–0.36)

cg20124410

13

107,333,224

0.58 (0–0.9)

0 (0–0.87)

0.32 (0–0.73)

cg10829391

14

101,069,717

0.95 (0.75–0.99)

0.59 (0–0.97)

0.87 (0.57–0.97)

cg26748794^*

16

88,804,052

0.97 (0.84–0.99)

0.59 (0–0.97)

0.89 (0.63–0.97)

0.67 (0.41–0.83)

0.69 (0.01–0.92)

0.67 (0.41–0.83)

cg20443278^*

17

77,962,099

0.62 (0–0.91)

0.78 (0–0.99)

0.96 (0.85–0.99)

0 (0–0.38)

0.24 (0–0.8)

0.83 (0.67–0.91)

cg14150973^*

19

40,950,432

0 (0–0.67)

0 (0–0.88)

0 (0–0.54)

0 (0–0.39)

0 (0–0.65)

0 (0–0.35)

cg17884856^*

20

44,334,913

0.93 (0.69–0.99)

0.84 (0–0.99)

0.88 (0.59–0.97)

0.89 (0.79–0.95)

0.05 (0–0.68)

0.59 (0.32–0.78)