Table 1 Bacterial strains

Rx1

Unencapsulated D39 S. pneumoniae derivative

[36, 44]

DP1004

Rx1 derivative, str-41, Sm^R

[29, 45]

FR183

DP1004 derivative, carrying φ1207.3, Sm^R, Em^R

[27]

FP40

FR183 derivative, carrying φ1207.3Δmef(A), Sm^R, Em^R, Cm^R

[27]

FR323

DP1004 derivative, spr0971ΔSpe, Sm^R, Spe^R

This study

FR324

DP1004 derivative, spr1023ΔKm, Sm^R, Km^R

This study

FR325

DP1004 derivative, spr1932ΔKm, Sm^R, Km^R

This study

FR358

FR323 derivative, carrying φ1207.3, Sm^R, Em^R, Spe^R

This study

FR359

FR324 derivative, carrying φ1207.3, Sm^R, Em^R, Spe^R

This study

FR360

FR325 derivative, carrying φ1207.3, Sm^R, Em^R, Spe^R

This study

FR355

FR323 derivative, carrying φ1207.3Δmef(A), Sm^R,Em^R, Cm^R, Spe^R

This study

FR356

FR324 derivative, carrying φ1207.3Δmef(A), Sm^R, Em^R, Cm^R, Spe^R

This study

FR357

FR325 derivative, carrying φ1207.3Δmef(A), Sm^R, Em^R, Cm^R, Spe^R

This study

FR335

FR323 derivative, spr0971ΔSpe, spr1023ΔKm, Sm^R, Spe^R, Km^R

This study

FR336

FR323 derivative, spr0971ΔSpe, spr1932ΔKm, Sm^R, Spe^R, Km^R

This study

FR337

FR325 derivative, spr1932ΔKm, Δspr1023 (in-frame), Sm^R, Km^R

This study

FR344

FR335 derivative, carrying φ1207.3, Sm^R, Em^R, Spe^R, Km^R

This study

FR345

FR336 derivative, carrying φ1207.3, Sm^R, Em^R, Spe^R, Km^R

This study

FR349

FR337 derivative, carrying φ1207.3, Sm^R, Em^R, Km^R

This study

FR346

FR335 derivative, carrying φ1207.3Δmef(A), Sm^R, Em^R, Cm^R, Spe^R, Km^R

This study

FR347

FR336 derivative, carrying φ1207.3Δmef(A), Sm^R, Em^R, Cm^R, Spe^R, Km^R

This study

FR348

FR337 derivative, carrying φ1207.3Δmef(A), Sm^R, Em^R, Cm^R, Km^R

This study

FR338

FR337 derivative, spr1932ΔKm, Δspr1023 (in-frame), spr0971ΔSpe, Sm^R, Km^R, Spe^R

This study

FR351

FR338 derivative, carrying φ1207.3, Sm^R, Em^R, Km^R, Spe^R

This study

FR350

FR338 derivative, carrying φ1207.3Δmef(A), Sm^R, Em^R, Cm^R, Km^R, Spe^R

This study