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Table 2 Erythromycin sensitivity

From: Predicted transmembrane proteins with homology to Mef(A) are not responsible for complementing mef(A) deletion in the mef(A)–msr(D) macrolide efflux system in Streptococcus pneumoniae

Strain Genotype Phenotypeb Erythromycin
MIC (µg/ml)
Chromosome Φ1207.3a
spr0971 spr1023 spr1932 mef(A) msr(D)
DP1004 + + + np np Sensitive 0.06
FR183 + + + + + Resistant 8
FP40 + + + + Resistant 4
FR323 + + np np Sensitive 0.06
FR324 + + np np Sensitive 0.06
FR325 + + np np Sensitive 0.06
FR358 + + + + Resistant 8
FR359 + + + + Resistant 8
FR360 + + + + Resistant 8
FR355 + + + Resistant 4
FR356 + + + Resistant 4
FR357 + + + Resistant 4
FR335 + np np Sensitive 0.06
FR336 + np np Sensitive 0.06
FR337 + np np Sensitive 0.06
FR344 + + + Resistant 8
FR345 + + + Resistant 8
FR349 + + + Resistant 8
FR346 + + Resistant 8
FR347 + + Resistant 8
FR348 + + Resistant 4
FR338 np np Sensitive 0.06
FR351 + + Resistant 8
FR350 + Resistant 4
  1. anp: Φ1207.3 phage not present
  2. bMIC interpretative standards: sensitive ≤ 0.25 µg/ml, intermediate = 0.5 µg/ml, and resistant ≥ 1 µg/ml