Fig. 1
From: CRISPR/Cas9 genome editing system confirms centriolin’s role in cytokinesis
Targeting of the CNTRL gene with CRISPR guide RNA. A Schematic showing the location of the CNTRL gene, represented as a red line, on the long arm of chromosome 9 (9q33.2). The 43 exons comprising the centriolin locus are shown below, along with the specific sequence within exon 3 that was targeted by the guide RNA in bold. The translational start codon is underlined. Adapted from the UCSC Genome Browser graphic. B The double-stranded DNA sequence that was cloned into the CRISPR vector is shown