Fig. 3
From: CRISPR/Cas9 genome editing system confirms centriolin’s role in cytokinesis
Disruption of the centriolin gene with CRISPR/Cas9 results in the accumulation of multinucleated cells. A The number of cells, size of nuclei, and percentage of multinucleated cells was recorded. The data represents three independent experiments. B and C Immunofluorescence image showing examples of multinucleated cells (B, arrows) and daughter cells with a persistent intercellular midbody bridge (C, arrow). Blue is DAPI stain and green is microtubules. Images were taken at 40× magnification