Table 2 Genotype and allele frequency of XRCC1 and NBN genes polymorphisms and the association with childhood ALL

XRCC1 rs1799782 G > A

 Genotype

  GG

45 (48.9%)

47 (51.1%)

–

1

–

–

  GA

0 (0.0%)

0 (0.0%)

–

–

–

–

  AA

5 (62.5%)

3 (37.5%)

0.465

0.574

0.130

2.545

 Dominant model

  GA + AA

5 (62.5%

3 (37.5%)

0.465

0.574

0.130

2.545

 Recessive model

  GG + GA

45 (48.9%)

47 (51.1%)

0.465

1.74

0.393

7.713

 Allele

  G

90 (48.9%)

94 (51.1%)

–

1

–

–

  A

10 (62.5%)

6 (37.5%)

0.297

0.574

0.201

1.646

NBN rs709816 A > G

 Genotype

  AA

21 (51.2%)

20 (48.8)

–

1

–

–

  AG

24 (52.2%)

22 (47.8%)

0.963

0.962

0.415

2.235

  GG

5 (38.5%)

8 (61.5%)

0.420

1.68

0.470

6.007

 Dominant model

  AG + GG

29 (49.2%)

30 (50.8%)

0.839

1.086

0.489

2.214

 Recessive model

  AA + AG

45 (51.7%)

42 (48.3%)

0.376

0.583

0.177

1.925

 Allele

  A

66 (51.5%)

62 (48.4%)

–

1

–

–

  G

34 (47.2%)

38 (52.7%)

0.556

1.190

0.667

2.121

NBN rs1805794 C > G

 Genotype

  CC

28 (53.8%)

24 (46.2%)

–

1

–

–

  CG

22 (45.8%)

26 (54.2%)

0.42

1.378

0.628

3.029

  GG

0 (0.0%)

0 (0.0%)

–

–

–

–

 Dominant model

  CG + GG

22 (45.8%)

26 (54.2%)

0.423

1.378

0.628

3.029

 Recessive model

  CC + CG

50 (50.0%)

50 (50.0%)

–

–

–

–

 Allele

  C

78 (51.3%)

74 (48.6)

–

1

–

–

  G

22 (45.8%)

26 (54.1%)

0.508

1.246

0.650

2.388

rs709816 by rs1805794

1.119

0.336

3.062

0.313

29.948