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Table 1 Absolute numbers and proportions of parasitized and non-parasitized G6PD deficient and normal RBCs

From: A fluorometric assay to determine the protective effect of glucose-6-phosphate dehydrogenase (G6PD) against a Plasmodium spp. infection in females heterozygous for the G6PD gene: proof of concept in Plasmodium falciparum

Experiment

G6PDn not infected RBCs (% of normal RBC)

G6PDn infected RBCs (% of normal RBC)

G6PDd not infected RBCs (% of deficient RBC)

G6PDd infected RBCs (% of deficient RBC)

Odds ratio (95% CI), p

Schizont Replicate#1

9,610 (98.0)

192 (2.0)

51,252 (99.6)

219 (0.4)

0.2 (0.18 to 0.26), < 0.001

Schizont Replicate#2

13,821 (97.9)

291 (2.1)

85,019 (99.6)

368 (0.4)

0.2 (0.18 to 0.24), < 0.001

Ring Replicate#1

10,517 (99.1)

97 (0.9)

88,575 (99.7)

223 (0.3)

0.3 (0.21 to 0.35), < 0.001

Ring Replicate#2

8,349 (99.1)

74 (0.9)

90,803 (99.8)

159 (0.2)

0.2 (0.15 to 0.26), < 0.001

Pooled

42,297 (98.5)

654 (1.5)

315,649 (99.7)

969 (0.3)

0.2 (0.18 to 0.22), < 0.001

  1. CI confidence interval, G6PDd G6PD deficient, G6PDn G6PD normal, RBC red blood cell