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Table 1 Preconception and trimester-wise Levothyroxine dosage administered in hypothyroid women

From: Levothyroxine dosages during pregnancy among hypothyroid women. An experience from a tertiary care center of Karachi, Pakistan, based on data from Maternal Hypothyroidism on Pregnancy Outcomes Study (MHPO-5)

Levothyroxine dosage (µg per day)
n = 280
Median (IQR)
P value*
Preconception dose
85.7 (55.3)
1st trimester dose
100.0 (69.6)
0.001
1st trimester dose
100.0 (69.6)
2nd trimester dose
100.0 (75.0)
 < 0.01
2nd trimester dose
100.0 (75.0)
3rd trimester dose
100.0 (96.4)
 < 0.01
  1. *P-Value calculated by Wilcoxon Signed Rank test