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Table 2 Difference of prescribed levothyroxine dosage among TSH groups according to preconception and trimester-wise status in hypothyroid women

From: Levothyroxine dosages during pregnancy among hypothyroid women. An experience from a tertiary care center of Karachi, Pakistan, based on data from Maternal Hypothyroidism on Pregnancy Outcomes Study (MHPO-5)

  Levothyroxine dosage in controlled TSH levels (≤ 2.5 uIU/mL)
Median (IQR)
Levothyroxine dosage in uncontrolled TSH Levels (≥ 2.5 uIU/mL)
Median (IQR)
P-value*
Preconception (n = 211) 85.7 (58.9)
n = 106
75.0 (50.0)
n = 105
0.20
First trimester (n = 153) 100.0 (72.3)
n = 70
71.4 (64.3)
n = 83
0.05
Second trimester (n = 178) 100.0 (75.8)
n = 90
100.0 (64.3)
n = 88
0.09
Third trimester (n = 214) 100.0 (100.0)
n = 117
100.0 (71.4)
n = 97
0.42
  1. *P-Value calculated by Mann Whitney Test