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Table 2 Difference of prescribed levothyroxine dosage among TSH groups according to preconception and trimester-wise status in hypothyroid women

From: Levothyroxine dosages during pregnancy among hypothyroid women. An experience from a tertiary care center of Karachi, Pakistan, based on data from Maternal Hypothyroidism on Pregnancy Outcomes Study (MHPO-5)

 

Levothyroxine dosage in controlled TSH levels (≤ 2.5 uIU/mL)

Median (IQR)

Levothyroxine dosage in uncontrolled TSH Levels (≥ 2.5 uIU/mL)

Median (IQR)

P-value*

Preconception (n = 211)

85.7 (58.9)

n = 106

75.0 (50.0)

n = 105

0.20

First trimester (n = 153)

100.0 (72.3)

n = 70

71.4 (64.3)

n = 83

0.05

Second trimester (n = 178)

100.0 (75.8)

n = 90

100.0 (64.3)

n = 88

0.09

Third trimester (n = 214)

100.0 (100.0)

n = 117

100.0 (71.4)

n = 97

0.42

  1. *P-Value calculated by Mann Whitney Test