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Fig. 1 | BMC Research Notes

Fig. 1

From: Structure-based design and construction of a synthetic phage display nanobody library

Fig. 1

Sequence and structural basis for synthetic library design. A cAbBCII10 amino acid sequence showing the CDRs (underlined) and randomized positions (highlighted in gray). B cAbBCII10 structure (PDB: 3DWT). CDRs 1, 2 and 3 are colored in blue, green, and red, respectively. Colored spheres in CDRs 1 and 2 represent the randomized positions, while gray spheres represent CDR positions that were kept fixed. C The final nucleotide sequence for the whole nanobody, including the NcoI and NotI cloning sites

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