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Table 1 Unique and novel essential genes in E. meningoseptica G4076

From: Computational characterization and analysis of molecular sequence data of Elizabethkingia meningoseptica

Protein product Protein name KEGG orthology EC Subcellular localization
Two component system
 WP_016198590.1 Response regulator transcription factor K07665 Cytoplasmic
 WP_016199055.1 LytTR family DNA-binding domain-containing protein K07705 Cytoplasmic
 WP_016198441.1 Response regulator transcription factor K07665 Cytoplasmic
 WP_016199099.1 LytTR family DNA-binding domain-containing protein K07705 Cytoplasmic
 WP_016200043.1 VanW family protein K18346 Unknown
 WP_016199769.1 Two-component sensor histidine kinase K07636 2.7.13.3 Cytoplasmic membrane
Beta-lactam resistance
 WP_016170088.1 Penicillin-binding protein 2a K05515 3.4.16.4 Cytoplasmic membrane
 WP_016170028.1 Transglycosylase domain-containing proteina K05366 2.4.1.129 Cytoplasmic membrane
DNA replication
 WP_016169884.1 Ribonuclease HI K03469 3.1.26.4 Unknown
 WP_016199473.1 DNA primase K02316 2.7.7.101 Cytoplasmic
 WP_019051072.1 DNA polymerase III subunit gamma/taua K02343 2.7.7.7 Cytoplasmic
 WP_016198779.1 DNA polymerase III subunit delta\′ K02341 2.7.7.7 Cytoplasmic
Homologous recombination
 WP_016199810.1 Holliday junction branch migration protein RuvA K03550 3.6.4.12 Cytoplasmic
 WP_016198560.1 Holliday junction branch migration DNA helicase RuvB K03551 3.6.4.12 Cytoplasmic
 WP_016200627.1 Recombination protein RecR K06187 Cytoplasmic
 WP_016199534.1 DNA replication and repair protein RecF K03629  
Translation
 WP_009085459.1 30S ribosomal protein S2a K02967 Cytoplasmic
 WP_016200426.1 30S ribosomal protein S9a K02996 Cytoplasmic
 WP_009087380.1 30S ribosomal protein S12a K02946 Cytoplasmic
 WP_009087378.1 30S ribosomal protein S7a K02992 Cytoplasmic
 WP_016197802.1 30S ribosomal protein S10a K02946 Cytoplasmic
 WP_009087341.1 50S ribosomal protein L4a K02926 Cytoplasmic
 WP_016197785.1 50S ribosomal protein L16a K02878 Cytoplasmic
 WP_009087327.1 50S ribosomal protein L14 K02874 Cytoplasmic
 WP_016197784.1 50S ribosomal protein L24 K02895 Cytoplasmic
 WP_009087314.1 30S ribosomal protein S5a K02988 Cytoplasmic
 WP_016197779.1 50S ribosomal protein L15 K02876 Cytoplasmic
 WP_016197776.1 30S ribosomal protein S13a K02952 Cytoplasmic
 WP_009087288.1 30S ribosomal protein S11a K02948 Cytoplasmic
 WP_016170211.1 30S ribosomal protein S4a K02986 Cytoplasmic
 WP_016170209.1 50S ribosomal protein L17 K02879 Cytoplasmic
 WP_016198862.1 30S ribosomal protein S16 K02959 Cytoplasmic
 WP_016200457.1 50S ribosomal protein L20 K02887 Cytoplasmic
 WP_016199408.1 30S ribosomal protein S1 K02945 Cytoplasmic
 WP_016200561.1 50S ribosomal protein L9 K02939 Cytoplasmic
ABC Transporters
 WP_016198610.1 ATP-binding cassette domain-containing proteina K09812 Cytoplasmic membrane
 WP_016198126.1 ABC transporter ATP-binding proteina K09810 7.6.2.- Cytoplasmic membrane
Protein export
 WP_026149261.1 Signal peptidase Ia K03100 3.4.21.89 Cytoplasmic membrane
Methane metabolism
 WP_016198134.1 Phosphoenolpyruvate carboxylasea K01595 4.1.1.31 Cytoplasmic
Base excision repair
 WP_016170024.1 Endonuclease III K10773 4.2.99.18 Cytoplasmic
Biotin metabolism
 WP_016199146.1 Dethiobiotin synthase K01935 6.3.3.3 Cytoplasmic
  1. aPotential therapeutic candidates as per FDA approved drugbank