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Fig. 2 | BMC Research Notes

Fig. 2

From: Identifying potential regulators of JAGGED1 expression in portal mesenchymal cells

Fig. 2

Examination of enrichment of potential regulators in portal mesenchymal cells. a SLUG was enriched in cluster #6 of the CS20 dataset (FDR-adjusted p value = 2.08 × 10–51). b SOX2 was not enriched in cluster #6 of the CS20 dataset (FDR-adjusted p value = 1.00). c EGR1 was enriched in cluster #6 of the CS20 dataset (FDR-adjusted p value = 5.91 × 10–22). d Comparison of JAGGED1 or SLUG expression in the cells of cluster #6 of the CS20 dataset as evaluated by Fisher’s exact test. Note that the percentage of SLUG-expressing cells was significantly higher in JAGGED1-expressing cells than in JAGGED1-nonexpressing cells (p = 1.95 × 10–4). e Comparison of JAGGED1 or EGR1 expression in the cells of cluster #6 of the CS20 dataset as evaluated by Fisher’s exact test. Note that the percentage of EGR1-expressing cells was significantly higher in JAGGED1-expressing cells than in JAGGED1-nonexpressing cells (p = 6.37 × 10–4). f SLUG was enriched in cluster #15 of the CS23 dataset (FDR-adjusted p value = 2.29 × 10–13). g SOX2 was not enriched in cluster #15 of the CS23 dataset (FDR-adjusted p value = 1). h EGR1 was enriched in cluster #15 of the CS23 dataset (FDR-adjusted p value = 9.51 × 10–6). i Comparison of JAGGED1 or SLUG expression in the cells of cluster #15 of the CS23 dataset as evaluated by Fisher’s exact test. Note that the percentage of SLUG-expressing cells was higher in JAGGED1-expressing cells than in JAGGED1-nonexpressing cells, although the difference was not statistically significant (p = 0.150). j Comparison of JAGGED1 or EGR1 expression in the cells in cluster #15 of the CS23 dataset as evaluated by Fisher’s exact test. Note that the percentage of EGR1-expressing cells was lower in JAGGED1-expressing cells than in JAGGED1-nonexpressing cells, although the difference was not statistically significant (p = 1.00)

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