Table 2 Pulmonary function parameters and lung ultrasound signals assessed pre- and post-therapist-oriented home rehabilitation
Variables | Pre-TOHR | Post-TOHR | Absolute delta | P-value |
|---|---|---|---|---|
Spirometry | ||||
FVC (% predicted) | 72.6 (65–89) | 74.5 (67–92) | 1.9 (0.4–3.2) | 0.06 |
FEV1 (% predicted) | 71.3 (64.1–83.7) | 74.1 (68–88) | 2.8 (0.2–5.3) | 0.07 |
FEV1/FVC (% predicted) | 99.2 (95.8–102) | 100 (99–104) | 1.5 (0.1–3.5) | 0.13 |
FEF25-75% (% predicted) | 67.3 (55.7–72.5) | 77.1 (63–127) | 6.5 (− 5.3 to 14.7) | 0.24 |
Impulse oscillometry | ||||
Fres (Hz) | 18.9 (12–27) | 11 (10–21) | − 5 (− 6.2 to − 1.3) | 0.002 |
Rm (cmH2O/L/s) | 4.44 (3.18–5.38) | 3.94 (2.57–4.91) | − 0.58 (− 1.5 to 0) | 0.091 |
R4 (cmH2O/L/s) | 5.27 (4.07–7.97) | 4 (2.85–6.03) | − 1.2 (− 4.3 to − 0.2) | 0.034 |
R4 (% predicted) | 150 (109–171) | 126 (89–151) | − 18 (− 44.3 to − 4) | 0.021 |
R6 (cmH2O/L/s) | 4.66 (3.29–5.62) | 3.82 (2.77–5.36) | − 0.86 (− 1.8 to − 0.1) | 0.034 |
R6 (% predicted) | 146 (109–170) | 128 (87.8–149) | − 23.5 (− 33.8 to − 0.5) | 0.014 |
R10 (cmH2O/L/s) | 4.55 (3.24–5.41) | 3.61 (2.69–4.92) | − 0.6 (− 2 to − 0.1) | 0.041 |
R10 (% predicted) | 144 (103–165) | 126 (91.3–140) | − 14 (− 38.5 to − 3.5) | 0.025 |
R20 (cmH2O/L/s) | 4.45 (3.03–5.14) | 3.55 (2.6–4.6) | − 0.6 (− 1.6 to 0.2) | 0.099 |
R20 (% predicted) | 128 (88–150) | 117 (80–137) | − 13.5 (− 35 to − 12.3) | 0.18 |
R4-R20 (cmH2O/L/s) | 1.18 (0.79–2.72) | 0.44 (0.2–0.79) | − 0.32 (− 2.2 to –0.03) | 0.021 |
AX (cmH2O/L) | 4 (2.33–5.22) | 2.17 (0.79–2.80) | − 1.2 (− 3.1 to − 0.2) | 0.002 |
Lung ultrasound | ||||
B-lines > 2 | 3.5 (0.5–8.8) | 2.5 (0.3–5.8) | − 1 (− 1.8 to 0) | 0.07 |
Coalescent B-lines | 0 (0–2.8) | 0 (0–2.8) | 0 (0–0) | 1 |
Subpleural consolidations | 0 (0–0) | 0 (0–0) | 0 (0–0) | 1 |
Aeration score (points) | 6 (0.5–15.8) | 4.5 (0.25–13.5) | − 1 (− 1.8 to 0) | 0.06 |