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Table 2 Pulmonary function parameters and lung ultrasound signals assessed pre- and post-therapist-oriented home rehabilitation

From: Can home rehabilitation impact impulse oscillometry and lung ultrasound findings in patients with scleroderma-associated interstitial lung disease? A pilot study

Variables Pre-TOHR Post-TOHR Absolute delta P-value
Spirometry     
 FVC (% predicted) 72.6 (65–89) 74.5 (67–92) 1.9 (0.4–3.2) 0.06
 FEV1 (% predicted) 71.3 (64.1–83.7) 74.1 (68–88) 2.8 (0.2–5.3) 0.07
 FEV1/FVC (% predicted) 99.2 (95.8–102) 100 (99–104) 1.5 (0.1–3.5) 0.13
 FEF25-75% (% predicted) 67.3 (55.7–72.5) 77.1 (63–127) 6.5 (− 5.3 to 14.7) 0.24
Impulse oscillometry     
 Fres (Hz) 18.9 (12–27) 11 (10–21) − 5 (− 6.2 to − 1.3) 0.002
 Rm (cmH2O/L/s) 4.44 (3.18–5.38) 3.94 (2.57–4.91) − 0.58 (− 1.5 to 0) 0.091
 R4 (cmH2O/L/s) 5.27 (4.07–7.97) 4 (2.85–6.03) − 1.2 (− 4.3 to − 0.2) 0.034
 R4 (% predicted) 150 (109–171) 126 (89–151) − 18 (− 44.3 to − 4) 0.021
 R6 (cmH2O/L/s) 4.66 (3.29–5.62) 3.82 (2.77–5.36) − 0.86 (− 1.8 to − 0.1) 0.034
 R6 (% predicted) 146 (109–170) 128 (87.8–149) − 23.5 (− 33.8 to − 0.5) 0.014
 R10 (cmH2O/L/s) 4.55 (3.24–5.41) 3.61 (2.69–4.92) − 0.6 (− 2 to − 0.1) 0.041
 R10 (% predicted) 144 (103–165) 126 (91.3–140) − 14 (− 38.5 to − 3.5) 0.025
 R20 (cmH2O/L/s) 4.45 (3.03–5.14) 3.55 (2.6–4.6) − 0.6 (− 1.6 to 0.2) 0.099
 R20 (% predicted) 128 (88–150) 117 (80–137) − 13.5 (− 35 to − 12.3) 0.18
 R4-R20 (cmH2O/L/s) 1.18 (0.79–2.72) 0.44 (0.2–0.79) − 0.32 (− 2.2 to –0.03) 0.021
 AX (cmH2O/L) 4 (2.33–5.22) 2.17 (0.79–2.80) − 1.2 (− 3.1 to − 0.2) 0.002
Lung ultrasound     
 B-lines > 2 3.5 (0.5–8.8) 2.5 (0.3–5.8) − 1 (− 1.8 to 0) 0.07
 Coalescent B-lines 0 (0–2.8) 0 (0–2.8) 0 (0–0) 1
 Subpleural consolidations 0 (0–0) 0 (0–0) 0 (0–0) 1
 Aeration score (points) 6 (0.5–15.8) 4.5 (0.25–13.5) − 1 (− 1.8 to 0) 0.06
  1. Results expressed as the median (interquartile range)
  2. TOHR: therapist-oriented home rehabilitation; FVC: forced vital capacity; FEV1: forced expiratory volume in one second; FEF25-75%: forced expiratory flow during the middle half of the FVC; Fres: resonance frequency; Rm: mean resistance between 4–20 Hz; R4: resistance at 4 Hz; R6: resistance at 6 Hz; R10: resistance at 10 Hz; R20: resistance at 20 Hz; R4-R20: heterogeneity of resistance between 4–20 Hz; AX: area under the reactance curve