Fig. 2

Immunostaining for CD138 and Kappa markers in B6 mouse tissues. a Lung had diffuse CD138 immunostaining of airway surface epithelium and alveolar type 2 and 1 epithelial cells (inset). b Lung. Kappa immunostaining was negative (inset). c, d Malignant peripheral nerve sheath tumor. Neoplastic cells had widespread CD138 immunostaining (c), whereas Kappa was negative in the tumor except for discrete small cellular aggregates of plasmacytes (d, inset, arrow). DAB chromogen (brown color) and hematoxylin counter stain (blue color), bar = 160 µm (a,b) and 40 µm (c, d)