Presepsin and platelet to lymphocyte ratio predict the progression of septic subclinical acute kidney injury to septic acute kidney injury: a pilot study

Table 2 Receiver operating characteristic curve analysis for predicting septic subclinical AKI to septic AKI progression

Variable	AUC	Cut-off	P value	Sensitivity (%)	Specificity (%)
Presepsin on Day 1 (pg/mL)	0.69	708.00	0.02	0.82	0.52
Presepsin on Day 2 (pg/mL)	0.69	1283.00	0.03	0.55	0.80
Presepsin on Day 3 (pg/mL)	0.60	872.00	0.35	0.57	0.64
Presepsin on Day 5 (pg/mL)	0.72	1262.00	0.03	0.59	0.89
ΔPresepsin Day 2—Day 1 (pg/mL)	0.50	13.00	0.96	0.66	0.50
ΔPresepsin Day 3—Day 1 (pg/mL)	0.53	− 228.00	0.79	0.57	0.62
ΔPresepsin Day 5—Day 1 (pg/mL)	0.50	− 423.00	1.00	0.61	0.50
GPS	0.57	2.00	0.34	0.55	0.57
iPS-GPS	0.61	1.00	0.13	0.76	0.43
NLR	0.55	8.89	0.48	0.45	0.76
iPS-NLR	0.53	2.00	0.63	0.29	0.86
PLR	0.67	368.66	0.03	0.71	0.62
iPS-PLR	0.54	0.00	0.58	0.34	0.76
PI	0.58	1.00	0.31	0.82	0.38
iPS-PI	0.58	1.00	0.26	0.66	0.48
PNI	0.60	26.08	0.27	0.58	0.67
iPS-PNI	0.61	2.00	0.06	0.29	1.00

AKI acute kidney injury, AUC area under the curve, GPS Glasgow Prognostic Score, iPS inflammation-presepsin score, NLR neutrophil to lymphocyte ratio, PLR platelet to lymphocyte ratio, PI Prognostic Index, PNI Prognostic Nutritional Index

ISSN: 1756-0500