Fig. 2From: Effects of end-stage osteoarthritis on markers of skeletal muscle Long INterspersed Element-1 activityL1 mRNA expression is higher in older participants regardless of limb. ORF1 mRNA expression (panel a) and gDNA content (panel b), L1 Promoter methylation status (panel c), and L1 chromatin accessibility (panel d). All variables in OA patients are presented in the surgical (SX) and control (CTL) thighs as fold-change from the young comparator group (Y). Different letters above bars indicate a significant difference between groups (p < 0.05), and all data are presented as mean ± standard deviation valuesBack to article page