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Table 1 Pro-inflammatory and vascular injury biomarkers

From: Whole-body inhalation of nano-sized carbon black: a surrogate model of military burn pit exposure

Analyte Function
IL-1β Cytokine: potent mediator of the inflammatory response; innate Th2 inflammatory response
IL-4 Cytokine: innate Th2 inflammatory response
IL-5 Cytokine: essential for eosinophil differentiation and survival; innate Th2 inflammatory response
IL-6 Cytokine: pro-inflammatory roles; chronic inflammation
IL-10 Cytokine: induced by inflammation, role in limiting immune response
IL-13 Cytokine: innate Th2 inflammatory response
IFN-γ Cytokine: important immunoregulatory functions; activator of macrophages
KC/GRO (CXCL1) Chemokine: role in inflammation and as a chemoattractant for neutrophils
TNFα Cytokine: innate Th2 inflammatory response
Adiponectin Regulates glucose levels & fatty acid breakdown; positive association with cardiovascular mortality
MCP1 (CCL2) Chemotactic for monocytes and basophils; associated with cardiovascular diseases and cognitive decline
sE-Selectin Role in immunoadhesion; systemic endothelial dysfunction
sICAM-1 Role in immunoadhesion; systemic endothelial dysfunction
TIMP1 Regulator of extracellular matrix synthesis and degradation; biomarker of fibrosis