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Fig. 1 | BMC Research Notes

Fig. 1

From: Capparis spinosa improves non-alcoholic steatohepatitis through down-regulating SREBP-1c and a PPARα-independent pathway in high-fat diet-fed rats

Fig. 1

Effect of Capparis spinosa fruit extract and fenofibrate on the body weight (a), liver weight (b), liver index (c), liver TG content (d), sterol regulatory element-binding protein 1c (SREBP1c) (e), acetyl-CoA carboxylase (ACC) (f), peroxisome proliferator-activated receptor α (PPARα) (g), carnitine palmitoyltransferase 1 (CPT1) (h) mRNA expression in NASH model rats during 12 weeks of treatment. Bars represent the mean ± SD of the variables in each group (n = 8). NC, normal control; HF, high fat; CS, Capparis spinosa; FENO, fenofibrate. *p < 0.05; **p < 0.01; ***p < 0.001 and ns: nonsignificant. I Significantly different from NC at end of week 6; II Significantly different from NC after 12 weeks and III significantly different between NC, HF + FENO, and HF + CS vs. HF at end of week 12 (p < 0.001)

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