Fig. 1
From: TAK1-inhibitors did not reduce disease burden in a Vκ*MYC model of multiple myeloma
Survival after start of treatment in the Vk*MYC 12653 MM mouse model injected with TAK1-inhibitors. A Kaplan-Meier survival analysis for mice injected with vehicle (DMSO), 15 g/kg NG25, 30 g/kg NG25, 15 g/kg 5Z-7, or 30 g/kg 5Z-7. Five animals were designated to each group, and one animal was excluded for each group due to lack of tumor development. Final group size (n) is given for each group. BKaplan-Meier survival analysis for mice injected with DMSO as control, 1 mg/kg NG25, and 15 mg/kg NG25. Five animals were designated to each group, and final group size (n) is given for each group. P-values are calculated with Mantel-Cox log rank test, and a P-value of <0.05 was rendered significant