Fig. 2From: TAK1-inhibitors did not reduce disease burden in a Vκ*MYC model of multiple myelomaM-spike levels (gamma/album (G/A) ratio) in the Vκ*MYC 12,653 MM mouse model injected with TAK1-inhibitors. A Mice injected with vehicle (DMSO), 15 \(\mu\)g/kg NG25, 30 \(\mu\)g/kg NG25, 15 \(\mu\)g/kg 5Z-7, or 30 \(\mu\)g/kg 5Z-7. No significant differences were observed when treatment groups were compared with vehicle in the same week (Two-way ANOVA with Tukey´s multiple comparisons test). B Mice injected with vehicle (DMSO), 1 mg/kg NG25, or 15 mg/kg NG25. No significant differences were observed when treatment groups were compared with vehicle in the same week (Two-way ANOVA with Tukey´s multiple comparisons test). A P-value of < 0.05 was rendered significant. Dots are individual animalsBack to article page