Fig. 2

Effects of pro-inflammatory conditions on neutrophil rolling adhesion. a Neutrophil rolling velocity as a function of shear stress under hyperglycemic (red) and diabetic cocktail (blue) conditions. (n = 66, 50, 48, 50, 39, 42, 35, 28 cells) b Neutrophil cell projection area as a function of shear stress under hyperglycemic (red) and diabetic cocktail (blue) conditions. c Mean cell area vs. mean rolling velocity at different shear stresses (0.17 Pa–1.24 Pa) shows two clusters, indicating cells chronically exposed to diabetic cocktail are smaller and roll faster. Statistical significance was tested by 1-way ANOVA, (ns) no significance, (*) p-value < 0.01, (**) p-value < 0.001, (***) p-value < 0.0001