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Table 1 Input parameters

From: Supporting dialysis policy for end stage renal disease (ESRD) in Indonesia: an updated cost-effectiveness model

Parameters

Value (mean/rate)

SE

Range

Distribution

References

Survival and transition probabilities

 CAPD to HD

0.067

0.020

0.058–0.081

Beta

Surendra et al. [16]

 HD to CAPD

0.007

0.002

0.002–0.001

Beta

Surendra et al. [16]

 Peritonitis complication

0.200

0.010

0.180–0.220

Beta

Gupta et al. [17]

 Vascular access complication

0.100

0.013

0.075–0.125

Beta

Xue et al. [18]

CAPD (survival)

 Year 1

0.800

0.006

0.788–0.812

Beta

Gunawan and Sakti [19]

 Year 2

0.720

0.008

0.704–0.736

Beta

Assumed*

 Year 3

0.600

0.009

0.582–0.617

Beta

Gunawan and Sakti [19]

 Year 4

0.570

0.009

0.542–0.577

Beta

Assumed

 Year 5

0.520

0.009

0.502–0.537

Beta

Gunawan and Sakti [19]

HD (survival)

 Year 1

0.824

0.006

0.811–0.837

Beta

Afiatin et al., [20]

 Year 2

0.706

0.008

0.690–0.722

Beta

Afiatin et al., [20]

 Year 3

0.621

0.009

0.604–0.638

Beta

Afiatin et al., [20]

 Year 4

0.580

0.009

0.563–0.598

Beta

Afiatin et al., [20]

 Year 5

0.553

0.009

0.536–0.571

Beta

Afiatin et al., [20]

Direct medical costs

 Pre-dialysis set-up_CAPD

16,010,564

165,562

15,686,062–16,335,065

Gamma

Hospital billing

 Pre-dialysis set-up_HD

16,150,823

2,337,311

11,569,693–20,731,952

Gamma

Hospital billing

 DMC_CAPD

142,328,780

6,008,598

135,173,358–149,484,201

Gamma

Hospital billing

 DMC_HD

120,289,134

3,650,725

108,512,280–132,065,987

Gamma

Hospital billing

 CC_CAPD

9,592,093

4,178,178

1,402,864–17,781,321

Gamma

Hospital billing

 CC_HD

27,173,929

7,158,016

13,144,217–41,203,640

Gamma

Hospital billing

Direct non-medical costs

 DNMC_CAPD

5,266,455

1,353,606

2,613,387–7,919,522

Gamma

Interview

 DNMC_HD

10,083,572

950,959

8,219,690–11,947,453

Gamma

Interview

Indirect costs

 ID_CAPD

7,196,578

1,535,788

4,186,434–10,206,722

Gamma

Interview

 ID_HD

10,858,993

968,098

8,961,519–12,756,466

Gamma

Interview

Utility

 U_CAPD

0.81

0.04

0.73–0.88

Beta

Interview

 U_HD

0.65

0.03

0.60–0.71

Beta

Interview

 U_CAPD_com

0.31

0.09

0.13–0.39

Beta

Afiatin et al. [11],

 U_HD_com

0.37

0.11

0.15–0.58

Beta

Afiatin et al. [11],

Discounting

 Cost

3%

   

HTA guideline [17]

 Effect

3%

   

HTA guideline [17]

  1. Costs are in IDR, DMC direct medical costs, CC complication cost, DNMC direct non-medical cost, ID indirect cost, U utility, complication.
  2. *Due to the data reporting limitation as newly published evidence, we assumed the standard error for CAPD is similar to HD, since there were no significant differences in terms of survival results