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Table 1 Dosing protocol for DP using carboplatin. Integer n from inequality (2) is 1. Interval between doses is 15 min

From: Erroneous detection of desensitization doses in the prevention of hypersensitivity reactions

DP step

fi (μg/minute)

fa (μg/minute)

fN (μg/minute)

fs (μg/minute)

1

1.6

–

1.65

3.3

2

4.2

0.9

1.65

3.3

3

8.3

1.7

1.65

3.3

4

16.6

0.1

1.65

3.3

5

41.6

0.3

1.65

3.3

6

83.3

2.5

1.65

3.3

7

166.6

1.7

1.65

3.3

8

333.3

6.6

1.65

3.3

9

833.3

0.8

1.65

3.3

10

1666.6

0.1

1.65

3.3

11

3333.3

0.3

1.65

3.3

12

26800

0.7

1.65

3.3

  1. In bold, DP steps where fa > fN and where HSR may occur