BMC Research Notes

Table 2 Dosing protocol for DP using infliximab. Integer n from inequality (2) is 1. Interval between doses is 15 min

From: Erroneous detection of desensitization doses in the prevention of hypersensitivity reactions

DP step	f_i (mg/minute)	f_a (mg/minute)	f_N(mg/minute)	f_s (mg/minute)
1	0.016	–	0.0165	0.033
2	0.06	0.0001	0.0165	0.033
3	0.2	0.002	0.0165	0.033
4	0.7	0.007	0.0165	0.033
5	2.4	0.02	0.0165	0.033
6	7.4	0.008	0.0165	0.033
7	24	0.06	0.0165	0.033
8	74	0.01	0.0165	0.033
9	240	0.6	0.0165	0.033
10	740	0.008	0.0165	0.033
11	2406	0.6	0.0165	0.033
12	7406	0.6	0.0165	0.033
13	16733	0.3	0.0165	0.033

In bold, DP steps where f_a > f_N and where HSR may occur

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ISSN: 1756-0500

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