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Table 1 Association between menin and clinicopathological features

From: Loss of tumor suppressor menin expression in high grade cholangiocarcinomas

 

Menin staining (IHC score)

Total

P-valuea

0

1

2

3

A

 Age (years)

n

%

n

%

n

%

n

%

n

 

   ≤ 50

18

56.25

3

9.38

7

21.88

4

12.5

32

0.1504

   > 50

40

61.54

15

23.1

6

9.23

4

6.15

65

B

 Sex

  F

25

59.52

7

16.7

8

19.05

2

4.76

42

0.4114

  M

33

60

11

20

5

9.09

6

10.91

55

C

 AJCC Stage

  II

22

52.38

6

14.3

8

19.05

6

14.29

42

0.3206

  III

14

63.64

6

27.3

1

4.55

1

4.55

22

  IVA

22

66.67

6

18.2

4

12.12

1

3.03

33

D

 Grade

n

%

n

%

n

%

n

%

n

 

  I

1

10

2

20

3

30

4

40

10

0.0005

  II

25

56.8

8

18

8

18.2

3

6.8

44

  III

32

74.4

8

19

2

4.7

1

2.3

43

E

 Fibrosis

  N

56

81.2

7

10

2

2.9

4

5.8

69

 < .0001

  Y

2

7.1

11

39

11

39.3

4

14.3

28

F

Grade

Patients without fibrosis

 I

1

12.5

2

25

2

25

3

37.5

8

 < .0001

 II

24

85.7

3

10.7

0

0

1

3.6

28

 III

31

93.9

2

6.1

0

0

0

0

33

G

Grade

Patients with fibrosis

  I

0

0

0

0

1

50

1

50

2

0.3829

  II

1

6.3

5

31

8

50

2

12.5

16

  III

1

10

6

60

2

20

1

10

10

  1. aFisher exact test