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Table 1 Baseline demographics and characteristics

From: A phase I open-label study of the safety and efficacy of apatinib (rivoceranib) administered to patients with advanced malignancies to improve sensitivity to pembrolizumab in the second- or later-line setting (APPEASE)

 

Rivoceranib + Pembrolizumab (n = 5)

Age, median (range), in years

65 (52–72)

Male, n (%)

4 (80%)

Diagnosis

 

 Urothelial carcinoma of the bladder

2 (40%)

 Gastric and gastroesophageal adenocarcinoma

3 (60%)

 MSI– High

0 (0%)

Sites of metastasis

 

 Lung

2 (40%)

 Lymph Node

2 (40%)

 Liver

1 (20%)

 Bone

1 (20%)

ECOG

 

  0

3 (60%)

  1

2 (40%)

Former smoker

2 (40%)

History of hypertension

3 (60%)

Prior cancer therapy

 

 Surgery

3 (60%)

  Radiation

4 (80%)

  Chemotherapy

5 (100%)

  Immunotherapy

3 (60%)

  Pembrolizumab

2 (40%)

  Targeted

3 (60%)