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  1. Content type: Research article

    Hygienic behavior (HB) enables honeybees to tolerate parasites, including infection with the parasitic mite Varroa destructor, and it is a well-known example of a quantitative genetic trait. The understanding of ...

    Authors: Tanja Gempe, Silke Stach, Kaspar Bienefeld, Marianne Otte and Martin Beye

    Citation: BMC Research Notes 2016 9:474

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  2. Content type: Short Report

    More than 50,000 adult and cord blood samples were collected in Tempus tubes and stored at the Norwegian Institute of Public Health Biobank for future use. In this study, we systematically evaluated and compar...

    Authors: Jeanette Aarem, Gunnar Brunborg, Kaja K. Aas, Kari Harbak, Miia M. Taipale, Per Magnus, Gun Peggy Knudsen and Nur Duale

    Citation: BMC Research Notes 2016 9:430

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  3. Content type: Research article

    Simple sequence repeats (SSRs) are defined as sequence repeat units between 1 and 6 bp that occur in both coding and non-coding regions abundant in eukaryotic genomes, which may affect the expression of genes....

    Authors: Karim Sorkheh, Angela S. Prudencio, Azim Ghebinejad, Mehrana Kohei Dehkordi, Deniz Erogul, Manuel Rubio and Pedro Martínez-Gómez

    Citation: BMC Research Notes 2016 9:336

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  4. Content type: Technical Note

    The egg is a vital part of the chicken developmental process and an important protein source for humans. Despite the chicken egg being a subject of intense research little attention has been given to the role ...

    Authors: Ben Wade, Michelle Cummins, Anthony Keyburn and Tamsyn M. Crowley

    Citation: BMC Research Notes 2016 9:283

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  5. Content type: Research article

    Next-generation sequencing (NGS) technology has paved the way for rapid and cost-efficient de novo sequencing of bacterial genomes. In particular, the introduction of PCR-free library preparation procedures (L...

    Authors: Christopher Huptas, Siegfried Scherer and Mareike Wenning

    Citation: BMC Research Notes 2016 9:269

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  6. Content type: Short Report

    The Rosaceae family encompasses numerous genera exhibiting morphological diversification in fruit types and plant habit as well as a wide variety of chromosome numbers. Comparative genomics between various Ros...

    Authors: Matteo Buti, Daniel J. Sargent, Khethani G. Mhelembe, Pietro Delfino, Kenneth R. Tobutt and Riccardo Velasco

    Citation: BMC Research Notes 2016 9:268

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  7. Content type: Short Report

    Tomato spotted wilt virus (TSWV; Tospovirus: Bunyaviridae) has been an economically important virus in the USA for over 30 years. However the complete sequence of only one TSWV isolate...

    Authors: Shunmugiah V. Ramesh and Hanu R. Pappu

    Citation: BMC Research Notes 2016 9:200

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  8. Content type: Technical Note

    The continuing increase in size and quality of the “short reads” raw data is a significant help for the quality of the assembly obtained through various bioinformatics tools. However, building a reference geno...

    Authors: Christelle Aluome, Grégoire Aubert, Susete Alves Carvalho, Marie-Christine Le Paslier, Judith Burstin and Dominique Brunel

    Citation: BMC Research Notes 2016 9:81

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  9. Content type: Research article

    The influences that different programs and conditions have on error rates of single-nucleotide polymorphism (SNP) analyses are poorly understood. Using Illumina short-read sequence data generated from Listeria mo...

    Authors: Arthur W. Pightling, Nicholas Petronella and Franco Pagotto

    Citation: BMC Research Notes 2015 8:748

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  10. Content type: Research article

    The sphingolipid glucosylceramide (GlcCer) and factors involved in the fungal GlcCer pathways were shown earlier to be an integral part of fungal virulence, especially in fungal replication at 37 °C, in neutr...

    Authors: Arpita Singh, Antonella Rella, John Schwacke, Caterina Vacchi-Suzzi, Chiara Luberto and Maurizio Del Poeta

    Citation: BMC Research Notes 2015 8:681

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  11. Content type: Research article

    Historically, identification of causal agents of disease has relied heavily on the ability to culture the organism in the laboratory and/or the use of pathogen-specific antibodies or sequence-based probes. How...

    Authors: Shea N. Gardner, Kenneth G. Frey, Cassie L. Redden, James B. Thissen, Jonathan E. Allen, Adam F. Allred, Matthew D. Dyer, Vishwesh P. Mokashi and Tom R. Slezak

    Citation: BMC Research Notes 2015 8:682

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  12. Content type: Research article

    Iron (Fe) and phosphorus (P) are essential mineral nutrients in plants. Knowledge regarding global changes in the abundance of Fe-responsive genes under Pi deficiency as well as the processes these genes are i...

    Authors: Wenfeng Li and Ping Lan

    Citation: BMC Research Notes 2015 8:555

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  13. Content type: Research article

    The genus Herbidospora comprises actinomycetes belonging to the family Streptosporangiaceae and currently contains five recognized species. Although other genera of this family often produce bioactive secondary m...

    Authors: Hisayuki Komaki, Natsuko Ichikawa, Akio Oguchi, Moriyuki Hamada, Tomohiko Tamura and Nobuyuki Fujita

    Citation: BMC Research Notes 2015 8:548

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  14. Content type: Technical Note

    Large population-based translational epigenetic studies are emerging due to recent technological advances that have made molecular analyses possible. For example, the Infinium HumanMethylation450 Beadchip (HM...

    Authors: Ee Ming Wong, JiHoon E. Joo, Catriona A. McLean, Laura Baglietto, Dallas R. English, Gianluca Severi, John L. Hopper, Roger L. Milne, Liesel M. FitzGerald, Graham G. Giles and Melissa C. Southey

    Citation: BMC Research Notes 2015 8:543

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  15. Content type: Research article

    MicroRNAs (miRNAs) are an abundant class of endogenous small RNA molecules that downregulate gene expression at the post-transcriptional level. They play important roles by regulating genes that control multip...

    Authors: Ilona Johansen and Rune Andreassen

    Citation: BMC Research Notes 2014 7:945

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  16. Content type: Research article

    Generally, the results of high throughput analyses contain information about gene expressions, and about exon expressions. Approximately 90% of primary protein-coding transcripts undergo alternative splicing i...

    Authors: Shafiul Alam, Huong Thi Thanh Phan, Mio Okazaki, Masahiro Takagi, Kozo Kawahara, Toshifumi Tsukahara and Hitoshi Suzuki

    Citation: BMC Research Notes 2014 7:934

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  17. Content type: Research article

    Insertions/deletions (indels) are the second most common type of genomic variant and the most common type of structural variant. Identification of indels in next generation sequencing data is a challenge, and ...

    Authors: Dalia H Ghoneim, Jason R Myers, Emily Tuttle and Alex R Paciorkowski

    Citation: BMC Research Notes 2014 7:864

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  18. Content type: Research article

    The giant panda (Ailuropoda melanoleuca) is an endangered species well-known for ingesting bamboo as a major part of their diet despite the fact that it belongs to order Carnivora. However, the giant panda’s draf...

    Authors: Jingwei Jiang, Hein Min Tun, Nathalie France Mauroo, AngelPo Yee Ma, San Yuen Chan and Frederick C Leung

    Citation: BMC Research Notes 2014 7:827

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  19. Content type: Correspondence

    We examined the performance of three RNA-Sequencing library preparation protocols as a function of RNA integrity, comparing gene expressions between heat-degraded samples to their high-quality counterparts. Th...

    Authors: Emily A Chen, Tade Souaiaia, Jennifer S Herstein, Oleg V Evgrafov, Valeria N Spitsyna, Danea F Rebolini and James A Knowles

    Citation: BMC Research Notes 2014 7:753

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  20. Content type: Research article

    Epigenetics is the study of gene expression changes that are not caused by changes in the deoxyribonucleic acid (DNA) sequence. DNA methylation is an epigenetic mark occurring in C–phosphate–G sites (CpGs) tha...

    Authors: Daniel B Martinez-Arguelles, Sunghoon Lee and Vassilios Papadopoulos

    Citation: BMC Research Notes 2014 7:534

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  21. Content type: Research article

    Syntrichia caninervis is a desiccation-tolerant moss and the dominant bryophyte of the Biological Soil Crusts (BSCs) found in the Mojave and Gurbantunggut deserts. Next generation high throughput sequencing techn...

    Authors: Bei Gao, Daoyuan Zhang, Xiaoshuang Li, Honglan Yang and Andrew J Wood

    Citation: BMC Research Notes 2014 7:490

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  22. Content type: Short Report

    De novo genome assembly can be challenging due to inherent properties of the reads, even when using current state-of-the-art assembly tools based on de Bruijn graphs. Often users are not bio-informaticians and, i...

    Authors: Basil Britto Xavier, Julia Sabirova, Moons Pieter, Jean-Pierre Hernalsteens, Henri de Greve, Herman Goossens and Surbhi Malhotra-Kumar

    Citation: BMC Research Notes 2014 7:484

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  23. Content type: Research article

    Substantial progress has been made in the identification of sequence elements that control mRNA splicing and the genetic variants in these elements that alter mRNA splicing (referred to as splicing quantitativ...

    Authors: Paul K Korir, Lisa Roberts, Raj Ramesar and Cathal Seoighe

    Citation: BMC Research Notes 2014 7:401

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  24. Content type: Research article

    Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous. Furthermore, public genetic databases conta...

    Authors: Michael G Campana, Nelly Robles García, Frank J Rühli and Noreen Tuross

    Citation: BMC Research Notes 2014 7:111

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