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Genomics

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  1. Content type: Research article

    The giant panda (Ailuropoda melanoleuca) is an endangered species well-known for ingesting bamboo as a major part of their diet despite the fact that it belongs to order Carnivora. However, the giant panda’s draf...

    Authors: Jingwei Jiang, Hein Min Tun, Nathalie France Mauroo, AngelPo Yee Ma, San Yuen Chan and Frederick C Leung

    Citation: BMC Research Notes 2014 7:827

    Published on:

  2. Content type: Correspondence

    We examined the performance of three RNA-Sequencing library preparation protocols as a function of RNA integrity, comparing gene expressions between heat-degraded samples to their high-quality counterparts. Th...

    Authors: Emily A Chen, Tade Souaiaia, Jennifer S Herstein, Oleg V Evgrafov, Valeria N Spitsyna, Danea F Rebolini and James A Knowles

    Citation: BMC Research Notes 2014 7:753

    Published on:

  3. Content type: Research article

    Epigenetics is the study of gene expression changes that are not caused by changes in the deoxyribonucleic acid (DNA) sequence. DNA methylation is an epigenetic mark occurring in C–phosphate–G sites (CpGs) tha...

    Authors: Daniel B Martinez-Arguelles, Sunghoon Lee and Vassilios Papadopoulos

    Citation: BMC Research Notes 2014 7:534

    Published on:

  4. Content type: Research article

    Syntrichia caninervis is a desiccation-tolerant moss and the dominant bryophyte of the Biological Soil Crusts (BSCs) found in the Mojave and Gurbantunggut deserts. Next generation high throughput sequencing techn...

    Authors: Bei Gao, Daoyuan Zhang, Xiaoshuang Li, Honglan Yang and Andrew J Wood

    Citation: BMC Research Notes 2014 7:490

    Published on:

  5. Content type: Short Report

    De novo genome assembly can be challenging due to inherent properties of the reads, even when using current state-of-the-art assembly tools based on de Bruijn graphs. Often users are not bio-informaticians and, i...

    Authors: Basil Britto Xavier, Julia Sabirova, Moons Pieter, Jean-Pierre Hernalsteens, Henri de Greve, Herman Goossens and Surbhi Malhotra-Kumar

    Citation: BMC Research Notes 2014 7:484

    Published on:

  6. Content type: Research article

    Substantial progress has been made in the identification of sequence elements that control mRNA splicing and the genetic variants in these elements that alter mRNA splicing (referred to as splicing quantitativ...

    Authors: Paul K Korir, Lisa Roberts, Raj Ramesar and Cathal Seoighe

    Citation: BMC Research Notes 2014 7:401

    Published on:

  7. Content type: Research article

    Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous. Furthermore, public genetic databases conta...

    Authors: Michael G Campana, Nelly Robles García, Frank J Rühli and Noreen Tuross

    Citation: BMC Research Notes 2014 7:111

    Published on:

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