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Medical Research Methodology

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  1. Content type: Research article

    Activity monitoring is important to establish accurate daily physical activity levels in children with cerebral palsy (CP). However, few studies address issues around inclusion or exclusion of step count data;...

    Authors: Nichola C. Wilson, Suzie Mudge and N. Susan Stott

    Citation: BMC Research Notes 2016 9:411

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  2. Content type: Research article

    A recent topic of interest in the blood transfusion literature is the existence of adverse effects of transfusing red cells towards the end of their storage life. This interest has been sparked by conflicting ...

    Authors: Jillian A. Patterson, Elizabeth A. Stuart and Jane B. Ford

    Citation: BMC Research Notes 2016 9:367

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  3. Content type: Research article

    Causal mediation analysis is often used to understand the impact of variables along the causal pathway of an occurrence relation. How well studies apply and report the elements of causal mediation analysis rem...

    Authors: Shao-Hsien Liu, Christine M. Ulbricht, Stavroula A. Chrysanthopoulou and Kate L. Lapane

    Citation: BMC Research Notes 2016 9:354

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  4. Content type: Research article

    In this study we explored the possibility of automating the PGP9.5 immunofluorescence staining assay for the diagnosis of small fiber neuropathy using skin punch biopsies. The laboratory developed test (LDT) w...

    Authors: Nathalie Van Acker, Michael Ragé, Ellen Sluydts, Michiel W. M. Knaapen, Martine De Bie, Maarten Timmers, Erik Fransen, Carla Duymelinck, Stefanie De Schepper, Praveen Anand, Theo Meert, Léon Plaghki and Patrick Cras

    Citation: BMC Research Notes 2016 9:280

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  5. Content type: Research article

    Critically appraising the quality of clinical practice guidelines (CPGs) is an essential element of evidence implementation. Critical appraisal considers the quality of CPG construction and reporting processes...

    Authors: Karen Grimmer, Shingai Machingaidze, Janine Dizon, Tamara Kredo, Quinette Louw and Taryn Young

    Citation: BMC Research Notes 2016 9:244

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  6. Content type: Research article

    Persons living with HIV (PLWH) and substance use/misuse experience significant barriers to engagement in HIV care at every step of the HIV care continuum including: (1) HIV testing and diagnosis (2) linkage to...

    Authors: Kamini E. Kuchinad, Heidi E. Hutton, Anne K. Monroe, Garrick Anderson, Richard D. Moore and Geetanjali Chander

    Citation: BMC Research Notes 2016 9:229

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  7. Content type: Correspondence

    Convergent validity is one type of validity that is commonly assessed for patient-reported outcome measures (PROMs). It is assessed by means of “hypothesis testing”: determining whether the scores of the instr...

    Authors: Inger L. Abma, Maroeska Rovers and Philip J. van der Wees

    Citation: BMC Research Notes 2016 9:226

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  8. Content type: Short Report

    Limitations in the primary studies constitute one important factor to be considered in the grading of recommendations assessment, development, and evaluation (GRADE) system of rating quality of evidence. Howev...

    Authors: Toshi A. Furukawa, Tomofumi Miura, Anna Chaimani, Stefan Leucht, Andrea Cipriani, Hisashi Noma, Hiroshi Mitsuyasu, Shegenobu Kanba and Georgia Salanti

    Citation: BMC Research Notes 2016 9:218

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  9. Content type: Short Report

    A cohort study was planned to evaluate vaccine immunogenicity and effect of malaria and helminth co-infections on the bivalent Human papilloma virus (HPV) vaccine. The study would involve self collected introi...

    Authors: Miriam Nakalembe, Twaha Mutyaba and Florence Mirembe

    Citation: BMC Research Notes 2016 9:170

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  10. Content type: Research Article

    During the last decade, the number of clinical trials conducted in sub-Saharan Africa has increased significantly which has helped to address priority health problems in the region. Navrongo health research ce...

    Authors: James Akazili, Samuel Chatio, Fabian Sebastian Achana, Abraham Oduro, Edmund W. Kanmiki and Frank Baiden

    Citation: BMC Research Notes 2016 9:139

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  11. Content type: Research article

    Pain intensities of patients are repeatedly measured by Visual Analog Scale (VAS) and Pain Vision (PV) in a clinical research. Two measurements by VAS and PV are performed at the same time. In order to evaluat...

    Authors: Fumiaki Kiyomi, Masako Nishikawa, Yoichiro Yoshida and Keita Noda

    Citation: BMC Research Notes 2016 9:115

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  12. Content type: Research article

    Missing data in a large scale survey presents major challenges. We focus on performing multiple imputation by chained equations when data contain multiple incomplete multi-item scales. Recent authors have pro...

    Authors: Catrin O. Plumpton, Tim Morris, Dyfrig A. Hughes and Ian R. White

    Citation: BMC Research Notes 2016 9:45

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  13. Content type: Research article

    Fishing communities are potentially suitable for Human immunodeficiency virus (HIV) efficacy trials due to their high risk profile. However, high mobility and attrition could decrease statistical power to dete...

    Authors: Andrew Abaasa, Gershim Asiki, Juliet Mpendo, Jonathan Levin, Janet Seeley, Leslie Nielsen, Ali Ssetaala, Annet Nanvubya, Jan De Bont, Pontiano Kaleebu and Anatoli Kamali

    Citation: BMC Research Notes 2015 8:815

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  14. Content type: Research article

    There is evidence that physicians’ prescription behavior is negatively affected by the extent of their interactions with pharmaceutical companies. In order to develop and implement policies and interventions f...

    Authors: Tamara Lotfi, Rami Z. Morsi, Nada Zmeter, Mohammad W. Godah, Lina Alkhaled, Lara A. Kahale, Hala Nass, Hneine Brax, Racha Fadlallah and Elie A. Akl

    Citation: BMC Research Notes 2015 8:720

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