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Molecular Biology

  1. Content type: Short Report

    FapR protein from the psychrotrophic species Exiguobacterium antarcticum B7 was expressed and purified, and subsequently evaluated for its capacity to bind to the promoter regions of the fabH1-fabF and fapR-plsX-

    Authors: Rafael A. Baraúna, Diego A. das Graças, Catarina I. P. Nunes, Maria P. C. Schneider, Artur Silva and Marta S. P. Carepo

    Citation: BMC Research Notes 2016 9:447

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  2. Content type: Technical Note

    Multiple sclerosis is caused by an autoimmune response resulting in demyelination and neural degeneration. The adult central nervous system has the capacity to remyelinate axons in part through the generation ...

    Authors: Karen D. Lariosa-Willingham, Elen S. Rosler, Jay S. Tung, Jason C. Dugas, Tassie L. Collins and Dmitri Leonoudakis

    Citation: BMC Research Notes 2016 9:419

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  3. Content type: Research article

    Influenza is an acute respiratory illness and has become a serious public health problem worldwide. The need to study the HA and NA genes in influenza A virus is essential since these genes frequently undergo ...

    Authors: Agustiningsih Agustiningsih, Hidayat Trimarsanto, Vivi Setiawaty, I. Made Artika and David Handojo Muljono

    Citation: BMC Research Notes 2016 9:423

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  4. Content type: Technical Note

    Quantitative (q) PCR by amplification of nucleic acid with a fluorescent dye is widely used. Selection of adequate PCR reagents and devices is relevant to achieve reliable and consistent data. Our main objecti...

    Authors: Jianxin Yang, Berit Kemps-Mols, Marijke Spruyt-Gerritse, Jacqueline Anholts, Frans Claas and Michael Eikmans

    Citation: BMC Research Notes 2016 9:292

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  5. Content type: Short Report

    Forage grasses of the African genus Urochloa (syn. Brachiaria) are the basis of Brazilian beef production, and there is a strong demand for high quality, productive and adapted forage plants. Among the approximat...

    Authors: Rebecca C. U. Ferreira, Letícia J. Cançado, Cacilda B. do Valle, Lucimara Chiari and Anete P. de Souza

    Citation: BMC Research Notes 2016 9:152

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  6. Content type: Short Report

    The Chinese mitten crab Eriocheir sinensis is an economically important decapod crustacean in China. Despite a widespread distribution and production in China, the resources of E. sinensis have experienced a dram...

    Authors: Jingjing Li, Xuyun Geng, Limei Chen and Jinsheng Sun

    Citation: BMC Research Notes 2016 9:105

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  7. Content type: Research article

    Diabrotica virgifera virgifera, western corn rootworm, is one of the most devastating species in North America. D. v. virgifera neonates crawl through the soil to locate the roots on w...

    Authors: Thais B. Rodrigues, Etsuko N. Moriyama, Hang Wang, Chitvan Khajuria and Blair D. Siegfried

    Citation: BMC Research Notes 2016 9:18

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  8. Content type: Research article

    Gastric cancers present late in life with advanced disease and carry a poor prognosis. Polo-like Kinase 1 (PLK1) is a mitotic kinase with regulatory functions during G2/M and mitosis in the cell cycle. In mamm...

    Authors: M. Dibb, N. Han, J. Choudhury, S. Hayes, H. Valentine, C. West, AD Sharrocks and Yeng S. Ang

    Citation: BMC Research Notes 2015 8:676

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  9. Content type: Technical Note

    Agarose hydrogels are widely used for three-dimensional cell scaffolding in tissue engineering and cell biology. Recently, molecular profiles have been obtained with extraction of a minimal volume of RNA using...

    Authors: Takahiro Ogura, Akihiro Tsuchiya, Tom Minas and Shuichi Mizuno

    Citation: BMC Research Notes 2015 8:644

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  10. Content type: Research article

    There is a need for strong and tightly regulated promoters to construct more reliable and predictable genetic modules for synthetic biology and metabolic engineering. For this reason we have previously constru...

    Authors: Hsin-Ho Huang, Christian Seeger, U. Helena Danielson and Peter Lindblad

    Citation: BMC Research Notes 2015 8:459

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  11. Content type: Short Report

    Recently, the orphan G-protein coupled receptor 83 (GPR83) was identified as a new participant in body weight regulation. This receptor is highly expressed in the hypothalamic arcuate nucleus and is regulated ...

    Authors: Anne Müller, Brinja Leinweber, Jana Fischer, Timo D Müller, Annette Grüters, Matthias H Tschöp, Vera Knäuper, Heike Biebermann and Gunnar Kleinau

    Citation: BMC Research Notes 2014 7:913

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  12. Content type: Research article

    Telomere length is indicative of biological age. Shorter telomeres have been associated with several disease and health states. There are inconsistencies throughout the literature amongst relative telomere len...

    Authors: Joshua Denham, Francine Z Marques and Fadi J Charchar

    Citation: BMC Research Notes 2014 7:877

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  13. Content type: Research article

    High grade serous ovarian cancer is one of the poorly characterized malignancies. This study aimed to elucidate the mutational events in Malaysian patients with high grade serous ovarian cancer by performing t...

    Authors: Nurul-Syakima Ab Mutalib, Saiful Effendi Syafruddin, Reena Rahayu Md Zain, AhmadZailani Hatta Mohd Dali, Ryia Illani Mohd Yunos, Sazuita Saidin, Rahman Jamal and Norfilza M Mokhtar

    Citation: BMC Research Notes 2014 7:805

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  14. Content type: Research article

    In plants, RNA- based gene silencing mediated by small RNAs functions at the transcriptional or post-transcriptional level to negatively regulate target genes, repetitive sequences, viral RNAs and/or transposo...

    Authors: Tuong Vi T Dang, Saskia Windelinckx, Isabelle M Henry, Barbara De Coninck, Bruno PA Cammue, Rony Swennen and Serge Remy

    Citation: BMC Research Notes 2014 7:655

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